ReviewMolecules and cells2022
Recent Developments in Correlative Super-Resolution Fluorescence Microscopy and Electron Microscopy.
Review in Molecules and cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- The Role of Confinement in Biomineralization.Chemical reviews · 2025Review
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- Advancing Nanomedicine Through Electron Microscopy: Insights Into Nanoparticle Cellular Interactions and Biomedical Applications.International journal of nanomedicine · 2025Review
- Dsg2 ectodomain organization increases throughout desmosome assembly.Cell adhesion & migration · 2024Article
- Illuminating cellular architecture and dynamics with fluorescence polarization microscopy.Journal of cell science · 2024Review
- Fluorescence super-resolution microscopy via fluctuation-based multi-route synergy.Biomedical optics express · 2024Article
- A nanoscale visual exploration of the pathogenic effects of bacterial extracellular vesicles on host cells.Journal of nanobiotechnology · 2024Article
- Emerging roles of cytoskeletal transport and scaffold systems in human viral propagation.Animal cells and systems · 2024Review
- Expansion microscopy applied to mono- and dual-species biofilms.NPJ biofilms and microbiomes · 2023Article
- Review
- Diversity of cells and signals in the cardiovascular system.The Journal of physiology · 2023Article
- Analyzing the cellular plasma membrane by fast and efficient correlative STED and platinum replica EM.Frontiers in cell and developmental biology · 2023Article
- Visualizing extracellular vesicle biogenesis in gram-positive bacteria using super-resolution microscopy.BMC biology · 2022Article
- Defining domain-specific orientational order in the desmosomal cadherins.Biophysical journal · 2022Article
- Development of Deep-Learning-Based Single-Molecule Localization Image Analysis.International journal of molecular sciences · 2022Review
- Emerging Biophysics Tools for Biologists.Molecules and cells · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recently developed correlative super-resolution fluorescence microscopy (SRM) and electron microscopy (EM) is a hybrid technique that simultaneously obtains the spatial locations of specific molecules with SRM and the context of the cellular ultrastructure by EM. Although the combination of SRM and EM remains challenging owing to the incompatibility of samples prepared for these techniques, the increasing research attention on these methods has led to drastic improvements in their performances and resulted in wide applications. Here, we review the development of correlative SRM and EM (sCLEM) with a focus on the correlation of EM with different SRM techniques. We discuss the limitations of the integration of these two microscopy techniques and how these challenges can be addressed to improve the quality of correlative images. Finally, we address possible future improvements and advances in the continued development and wide application of sCLEM approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.