ArticleVirology2022
American alligators are capable of West Nile virus amplification, mosquito infection and transmission.
Article in Virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Mosquito-borne viral infections: veterinary diagnostic approach with a One Health perspective.Journal of clinical microbiology · 2026Review
- Detection and genomic characterization of West Nile virus lineage 2 in captive harbor seals in southern Italy.Frontiers in microbiology · 2026Article
- Tissue tropism, pathology, and pathogenesis of West Nile virus infection in saltwater crocodile (Crocodylus porosus).PLoS neglected tropical diseases · 2025Article
- Natural fatal infection of Tembusu virus in bottlenose dolphins in Thailand.Scientific reports · 2025Article
- African lineage 1a West Nile virus isolated from crocodiles exhibits low neuroinvasiveness in mice.The Journal of general virology · 2024Article
- WNV and SLEV coinfection in avian and mosquito hosts: impact on viremia, antibody responses, and vector competence.Journal of virology · 2024Article
- The Alligator and the Mosquito: North American Crocodilians as Amplifiers of West Nile Virus in Changing Climates.Microorganisms · 2024Article
- Culex erraticus (Diptera: Culicidae) utilizes gopher tortoise burrows for overwintering in North Central Florida.Journal of medical entomology · 2024Article
- A chimeric vaccine protects farmed saltwater crocodiles from West Nile virus-induced skin lesions.NPJ vaccines · 2023Article
- Aquatic Flaviviruses.Journal of virology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
West Nile virus (WNV) overwintering is poorly understood and likely multifactorial. Interest in alligators as a potential amplifying host arose when it was shown that they develop viremias theoretically sufficient to infect mosquitoes. We examined potential ways in which alligators may contribute to the natural ecology of WNV. We experimentally demonstrated that alligators are capable of WNV amplification with subsequent mosquito infection and transmission capability, that WNV-infected mosquitoes readily infect alligators and that water can serve as a source of infection for alligators but does not easily serve as in intermediate means for transmission between birds and alligators. These findings indicate potential mechanisms for maintenance of WNV outside of the primary bird-mosquito transmission cycle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.