Evidence map›Paper›PMID 35114198›Full record

Observational studyJournal of immunological methods2022

Evaluation of circulating leucocyte populations both in subjects with previous SARS-COV-2 infection and in healthy subjects after vaccination.

Vincenzo Grimaldi, Giuditta Benincasa, Giusi Moccia, Annunziata Sansone, Giuseppe Signoriello, Claudio Napoli

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of immunological methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Vaccines · 2024
    Article
  3. Review
  4. Observational
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vincenzo GrimaldiU.O.C. Division of Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology. Clinical Department of Internal Medicine and Specialistic Units, University of Campania "L. Vanvitelli", 80138 Naples, Italy. Electronic address: vincenzo.grimaldi@policliniconapoli.it.
Giuditta BenincasaDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Giusi MocciaU.O.C. Division of Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology. Clinical Department of Internal Medicine and Specialistic Units, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
Annunziata SansoneU.O.C. Division of Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology. Clinical Department of Internal Medicine and Specialistic Units, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
Giuseppe SignorielloStatistical Unit, Department of Mental Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Claudio NapoliU.O.C. Division of Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology. Clinical Department of Internal Medicine and Specialistic Units, University of Campania "L. Vanvitelli", 80138 Naples, Italy; Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate immune mechanisms are central players in response to the binding of pathogens to pattern-recognition receptors providing a crucial initial block on viral replication. Moreover, innate immune response mobilizes cells of the cellular-mediated immune system, which develop into effector cells that promote viral clearance. Here, we observed circulating leukocyte T cell response in healthy subjects, COVID-19 infected, and in healthy vaccinated subjects. We found a significant CD8

Indexed as

AdultAgedCase-Control StudiesCD4-CD8 RatioCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCOVID-19COVID-19 VaccinesCross-Sectional StudiesFemaleHealthy VolunteersHumansImmunity, InnateImmunogenicity, VaccineImmunophenotypingMaleCOVID-19 VaccinesCOVID-19 infectionCOVID-19 mRNA BNT162b2 (Pfizer-BioNTech) vaccineFlow cytometry characterizationT cell immune response

Identifiers

PMID35114198
PMCPMC8802555
OpenAlexW4210263702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.