ArticleCirculation research2022
Trajectories of Blood Pressure in Midlife Women: Does Menopause Matter?
Article in Circulation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
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Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Is hypertension negatively associated with memory performance in women during climacteric? A systematic review.BMC women's health · 2025Pooled it
- The acute effect of two exercise modalities on neurocognitive responses in postmenopausal women: A randomized controlled trial.Experimental physiology · 2026Trial
- Effect of Exercise Modalities on Post-Exercise Hypotension in Normotensive Postmenopausal Women: A Randomized Controlled Trial on Vasomotor Symptoms Influence.European journal of sport science · 2025Trial
- Microvascular endothelial function is blunted in postmenopausal females with frequent hot flushes.Experimental physiology · 2026Article
- Beyond BMI in interpreting sex-specific blood pressure trajectories: a comment on Kawasoe et al.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Trajectories of blood pressure and influencing factors across menopause: A longitudinal cohort study.American journal of preventive cardiology · 2026Article
- Reply to: "Comment on 'Sex-specific trajectories of blood pressure and pulse pressure across body mass index categories: a descriptive study based on 13-year health checkup data".Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Reply to: "Beyond BMI in interpreting sex-specific blood pressure trajectories: a comment on Kawasoe et al." [1].Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Comment on "Sex-specific trajectories of blood pressure and pulse pressure across body mass index categories: a descriptive study based on 13-year health checkup data".Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Mechanisms of Hypertension in Women: Interactions Between Vascular Ageing, Metabolic Dysfunction, and Hormonal Regulation.Biomedicines · 2026Review
- The Neurology of Menopause.Current neurology and neuroscience reports · 2026Review
- Heterogeneity in blood pressure and weight trajectories and associated mortality risk among hypertensive patients in rural South Africa: findings from cluster analysis of longitudinal clinical record linkage data.BMC public health · 2026Article
- Sex-specific trajectories of blood pressure and pulse pressure across body mass index categories: a descriptive study based on 13-year health checkup data.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Cardiometabolic changes in the menopause transition.Menopause (New York, N.Y.) · 2026Article
- Perimenopause as an obesogenic sensitive period: Contributions to elevated cardiovascular risk.American journal of preventive cardiology · 2026Article
- Exploring the relationship between reproductive aging, arterial stiffness, and cardiorespiratory fitness in women after menopause.Physiological reports · 2026Article
- Incidence of hypertension and factors associated with blood pressure control among older adults living with HIV in Western Kenya: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Novel Advances in Our Understanding of Sex-Dependent Control of Blood Pressure.Annual review of physiology · 2026Review
- Evaluation of Cardiovascular Effects of the Hydroalcoholic Fruit Extract ofCardiovascular & hematological disorders drug targets · 2026Article
- Association of female reproductive traits with altered aging trajectories: Insights from genetic and observational analyses.Cell reports. Medicine · 2025Observational
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7 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundWhether changes in blood pressure (BP) over women's midlife are more driven by chronological aging or the menopause transition has been debated. We sought to determine whether women can be classified into distinct trajectory groups based on pattern and level of systolic BP (SBP), diastolic BP, pulse pressure (PP), and mean arterial pressure (MAP) over the menopause transition, and to assess whether menopause-related factors predict the group and level of BP measures.
methodsParticipants were from the SWAN (Study of Women's Health Across the Nation). Group-based trajectory modeling was used to identify women who shared distinct BP trajectories over time relative to menopause onset and to assess associations of menopause-related factors with trajectory group and level of BP measures. An accelerated rise relative to menopause onset suggests a menopause contribution.
resultsThe study included 3302 multiracial and multiethnic women with BP measures over 17 follow-up visits (baseline age [SD]: 46.3 [2.7]). Women were classified into either low, medium, or high trajectory group in each BP measure. The low SBP, PP, and MAP trajectories (in 35%, 53%, and 28% of the cohort, respectively) were rising slowly before menopause but showed a significant accelerated rise 1 year after menopause, indicating a menopause contribution. The remaining BP trajectories were rising up until menopause and either continued with the same rise or declined after menopause. A younger menopause age predicted the low SBP, PP, and MAP trajectories. A greater follicle-stimulating hormone level predicted lower SBP and PP levels, while vasomotor symptoms occurrence predicted higher SBP, PP, and MAP levels over time. Estradiol did not predict trajectory or level of any BP measure.
conclusionsDistinct BP trajectories over the menopause transition exist that revealed a group of women whose SBP, PP, and MAP trajectories are consistent with a menopause contribution. Our findings support frequent monitoring of BP during the menopause transition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.