Evidence map›Paper›PMID 35113519›Full record

ArticleACS applied bio materials2022

Green and Facile Synthesis of Pullulan-Stabilized Silver and Gold Nanoparticles for the Inhibition of Quorum Sensing.

Mohammadreza Ghaffarlou, Sedef İlk, Hamideh Hammamchi, Feyza Kıraç, Meltem Okan, Olgun Güven, Murat Barsbay

Open access · hybridAbstract read
In one paragraph

Article in ACS applied bio materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mohammadreza GhaffarlouDepartment of Chemistry, Hacettepe University, Beytepe, Ankara 06800, Turkey.
Sedef İlkFaculty of Medicine, Department of Immunology, Niǧde Ömer Halisdemir University, Niǧde 51240, Turkey.
Hamideh HammamchiDepartment of Biology, Hacettepe University, Beytepe, Ankara 06800, Turkey.
Feyza KıraçDepartment of Chemistry, Hacettepe University, Beytepe, Ankara 06800, Turkey.
Meltem OkanDepartment of Micro and Nanotechnology, Middle East Technical University, Ankara 06800, Turkey.
Olgun GüvenDepartment of Chemistry, Hacettepe University, Beytepe, Ankara 06800, Turkey.
Murat BarsbayDepartment of Chemistry, Hacettepe University, Beytepe, Ankara 06800, Turkey.ORCID 0000-0003-0788-4446
Hacettepe University · TRMiddle East Technical University · TRNiğde Ömer Halisdemir Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pullulan (Pull) decorated with monodisperse Ag and Au nanoparticles (NPs) was synthesized by a simple and green method. Samples were characterized by FTIR, UV-vis, NMR, XRD, TGA, SEM, XPS, DLS, and TEM. SEM images showed highly oriented microforms reported for the first time for Pull, because of the supramolecular self-assembling behavior of Pull chains. Antimicrobial and quorum sensing (QS) inhibition activities were tested against six pathogen bacteria and reporter and biomonitor strain. Pull decorated with NPs, in particular, Ag-modified ones, outperformed pristine Pull. The cell proliferation was tested with an MTT assay. NPs-decorated Pull was studied for the first time as an inhibitory agent against bacterial signal molecules and found to be a good candidate. The promising performance of AgNPs@Pull compared to the commercial antibiotic gentamicin showed that it has great potential as a therapeutic approach to overcome the bacterial resistance that has developed against conventional antibiotics.

Indexed as

Metal NanoparticlesSilverAnti-Bacterial AgentsBacteriaGlucansGoldQuorum SensingAnti-Bacterial AgentsGlucansGoldpullulanSilverAg and Au nanoparticlesantimicrobial activitypullulanquorum sensing inhibition activitysupramolecular self-assembly

Identifiers

PMID35113519
PMCPMC8895461
OpenAlexW4210504818

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.