Evidence map›Paper›PMID 35113370›Full record

ArticleEnvironmental science and pollution research international2022

Association between urinary cadmium concentrations and liver function in adolescents.

Zining Xu, Zhenkun Weng, Jingjia Liang, Qian Liu, Xin Zhang, Jin Xu, Cheng Xu, Aihua Gu

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Toxics · 2026
    Article
  2. Article
  3. Review
  4. Mechanisms of Metal-Induced Hepatic Inflammation.Current environmental health reports · 2024
    Review
  5. Article
  6. Toxicity Tolerance in the Carcinogenesis of Environmental Cadmium.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Zining XuThe Second Clinical Medical School of Nanjing Medical University, Nanjing Medical University, Nanjing, 211166, People's Republic of China.
Zhenkun WengState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, People's Republic of China.
Jingjia LiangState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, People's Republic of China.
Qian LiuState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, People's Republic of China.
Xin ZhangState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, People's Republic of China.
Jin XuState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, People's Republic of China.
Cheng XuState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, People's Republic of China. chengxu@njmu.edu.cn.ORCID http://orcid.org/0000-0001-7576-9998
Aihua GuState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, 211166, People's Republic of China. aihuagu@njmu.edu.cn.
Nanjing Medical University · CNMinistry of Education · KRNanjing Maternity and Child Health Care Hospital · CNNorthern Jiangsu People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence from previous studies has shown that exposure to cadmium (Cd) is associated with cardiovascular disease, kidney disease, and osteoporosis, but the effects of Cd on liver toxicity in adolescents are unclear. The data of 4411 adolescents who participated in the US The National Health and Nutrition Examination Survey (NHANES) during 1999-2016 was analyzed. Liver function was indicated by the levels of alanine aminotransferase (ALT) and aspartate amino transferase (AST). The associations between the levels of urinary Cd and liver function were evaluated using multivariate logistic regression models adjusted for covariates. The results showed that the odds ratios of ALT and AST in the highest quartiles of urinary Cd were 1.40 (95% confidence interval [CI], 1.07-1.82) and 1.64 (95% CI, 1.10-2.44), respectively, compared with the lowest quartiles, which were similar to using urinary creatinine as the covariate. We also found linear regression of associations of urinary Cd with elevated ALT and AST levels in boys. In addition, one augmented urinary Cd concentration unit (Log

Indexed as

CadmiumLiverAdolescentAlanine TransaminaseAspartate AminotransferasesHumansMaleNutrition SurveysAlanine TransaminaseAspartate AminotransferasesCadmiumCadmiumC-reactive proteinHDL cholesterolLiver functionNHANES

Identifiers

PMID35113370
OpenAlexW4210414805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.