Evidence map›Paper›PMID 35113283›Full record

ArticleThe international journal of cardiovascular imaging2022

Left atrial remodeling and the prognostic value of feature tracking derived left atrial strain in patients with light-chain amyloidosis: a cardiovascular magnetic resonance study.

Zekun Tan, Yuelong Yang, Xinyi Wu, Sheng Li, Liwen Li, Liye Zhong, Qiongwen Lin, Hongwen Fei, Pengjun Liao, Wenjian Wang and 1 more

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In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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  16. Left atrial remodelling,  and image-based coronary physiology.The international journal of cardiovascular imaging · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zekun Tan *The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Yuelong Yang *The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Xinyi WuDepartment of Radiology, Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Sheng LiSchool of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Liwen LiDepartment of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Liye ZhongDepartment of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Qiongwen LinDepartment of Adult Echocardiography, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medicine Sciences, Guangzhou, Guangdong, China.
Hongwen FeiDepartment of Adult Echocardiography, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medicine Sciences, Guangzhou, Guangdong, China.
Pengjun LiaoDepartment of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Wenjian Wang *The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. wwjph@126.com.
Hui Liu *The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. liuhuijiujiu@gmail.com.ORCID http://orcid.org/0000-0003-0148-0125
Guangdong Academy of Medical Sciences · CNSecond Affiliated Hospital of Guangzhou Medical University · CNZhujiang Hospital · CN

Funding

Key R&D Program of Guangdong Province 2018B030339001National Natural Science Foundation of China 81974262Natural Science Foundation of Guangdong Province 2020A1515010650
6 · The paper itself

Abstract

Systemic light-chain (AL) amyloidosis is characterized by the aggregation of misfolded immunoglobulin light chain, predominantly infiltrating in the heart, including left atrium (LA). LA remodeling, such as increased interatrial septal thickness and enlarged size, has been observed. However, LA strain assessed by cardiac magnetic resonance feature tracking (CMR-FT) and its prognostic role remains to be further determined. Using CMR, the current study sought to investigate the characteristic of LA remodeling and the prognostic value of LA strain in patients with AL. Eighty-seven consecutive patients who underwent CMR with histologically confirmed systemic light-chain amyloidosis were retrospectively enrolled. LA strain parameters were analyzed based on CMR-FT algorithm. Amyloid infiltration and burden loads were assessed with CMR late gadolinium enhancement (LGE) and extracellular volume (ECV). Patients were categorized according to the extent of amyloid infiltration in cardiac myocardium. The primary endpoint was defined as all-cause mortality. The prognosis value of LA strain indices was evaluated using Cox proportional hazards regression and Kaplan-Meier curves. Interatrial septal thickness (3 [2-5] vs. 4 [3-5] mm, p = 0.007) and indexed LA volume (34.6 [26.9-44.6] vs. 50.5 [36.1-58.5] ml/m

Indexed as

Cardiac amyloidosisCardiovascular magnetic resonanceFeature trackingLeft atrialStrain

Identifiers

PMID35113283
OpenAlexW4210697433

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.