Evidence map›Paper›PMID 35113189›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Bullying in clinical high risk for psychosis participants from the NAPLS-3 cohort.

Amy Braun, Lu Liu, Carrie E Bearden, Kristin S Cadenhead, Barbara A Cornblatt, Matcheri Keshavan, Daniel H Mathalon, Thomas H McGlashan, Diana O Perkins, Larry J Seidman and 6 more

Abstract read
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In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Amy BraunDepartment of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada.ORCID http://orcid.org/0000-0002-6116-3597
Lu LiuDepartment of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada.
Carrie E BeardenDepartments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA.
Kristin S CadenheadDepartment of Psychiatry, UCSD, San Diego, CA, USA.
Barbara A CornblattDepartment of Psychiatry, Zucker Hillside Hospital, Long Island, NY, USA.
Matcheri KeshavanDepartment of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, USA.
Daniel H MathalonDepartment of Psychiatry, UCSF, and SFVA Medical Center, San Francisco, CA, USA.
Thomas H McGlashanDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Diana O PerkinsDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Larry J SeidmanDepartment of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, USA.
William StoneDepartment of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, USA.
Ming T TsuangDepartment of Psychiatry, UCSD, San Diego, CA, USA.
Elaine F WalkerDepartments of Psychology and Psychiatry, Emory University, Atlanta, GA, USA.
Scott W WoodsDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Tyrone D CannonDepartment of Psychology, Yale University, New Haven, CT, USA.
Jean AddingtonDepartment of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada. jmadding@ucalgary.ca.
Beth Israel Deaconess Medical Center · USUniversity of Calgary · CAYale University · USUniversity of California San Diego · USEmory University · USUniversity of North Carolina at Chapel Hill · USZucker Hillside Hospital · US

Funding

5/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082004 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PERKINS, DIANA O. · 2008 to 2018
$7.5M
6 · The paper itself

Abstract

purposeBullying is associated with a heightened risk for poor outcomes, including psychosis. This study aimed to replicate previous findings on bullying prevalence in clinical high-risk (CHR) individuals, to assess the longitudinal course of clinical and functional variables between bullied and non-bullied CHR and the association of bullying with premorbid functioning, clinical outcome, transition to psychosis and risk of violence.

methodsThe sample consisted of 691 CHR participants and 96 healthy controls. Participants reported whether they had experienced bullying and how long it had lasted. Assessments included DSM-5 diagnoses, attenuated psychotic symptoms, negative symptoms, social and role functioning, depression, stress, premorbid functioning, and risk of violence. The bullied and non-bullied CHR groups were compared at baseline and further longitudinally on clinical and functioning variables and transition to psychosis.

resultsBullying was more prevalent among CHR individuals than healthy controls. Bullied CHR had a higher prevalence of PTSD and more severe depression and stress at baseline than non-bullied CHR. There was no impact of bullying on clinical and functional variables over time. Bullying was not related to final clinical status or transition to psychosis. However, bullied participants had poorer premorbid functioning and a greater risk of violence.

conclusionWhile bullying may not impact the likelihood of CHR individuals to transition to psychosis, it may be a risk factor for development of the at-risk state and may be related to a greater risk of violence. Future studies should consider bullying perpetration among CHR individuals.

Indexed as

BullyingPsychotic DisordersCohort StudiesHumansProdromal SymptomsRisk FactorsBullyingClinical high riskPsychosisPsychotic symptomsViolence risk

Identifiers

PMID35113189
OpenAlexW4210539419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.