Evidence map›Paper›PMID 35113168›Full record

SynthesisActa orthopaedica2022

The effect of patient and prosthesis factors on revision rates after total knee replacement using a multi-registry meta-analytic approach.

Peter L Lewis, Annette W-Dahl, Otto Robertsson, Michelle Lorimer, Heather A Prentice, Stephen E Graves, Elizabeth W Paxton

Abstract readMeta-Analysis
In one paragraph

Synthesis in Acta orthopaedica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter L LewisAustralian Orthopaedic Association National Joint Replacement Registry, South Australian Health and Medical Research Institute, Adelaide, SA Australia; Lund University, Faculty of Medicine, Clinical Science Lund, Department of Orthopedics, Lund, Sweden. plewis@aoanjrr.org.au.
Annette W-DahlSwedish Knee Arthroplasty Register, Lund, Sweden; Lund University, Faculty of Medicine, Clinical Science Lund, Department of Orthopedics, Lund, Sweden. annette.w-dahl@med.lu.se.
Otto RobertssonSwedish Knee Arthroplasty Register, Lund, Sweden; Lund University, Faculty of Medicine, Clinical Science Lund, Department of Orthopedics, Lund, Sweden. otto.robertsson@med.lu.se.
Michelle LorimerAustralian Orthopaedic Association National Joint Replacement Registry, South Australian Health and Medical Research Institute, Adelaide, SA Australia. michelle.lorimer@sahmri.com.
Heather A PrenticeSurgical Outcomes and Analysis, Kaiser Permanente, San Diego, CA, USA. Heather.Prentice@KP.org.
Stephen E GravesAustralian Orthopaedic Association National Joint Replacement Registry, South Australian Health and Medical Research Institute, Adelaide, SA Australia. segraves@aoanjrr.org.au.
Elizabeth W PaxtonSurgical Outcomes and Analysis, Kaiser Permanente, San Diego, CA, USA. liz.w.paxton@kp.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCharacteristics of patients receiving total knee arthroplasty (TKA) and prostheses used vary between regions and change with time. How these practice variations influence revision remains unclear. We combined registry data for better understanding of the impact of variation, which could potentially improve revision rates. PATIENTS AND

methodsWe used data from 2003 to 2019 for primary TKA from arthroplasty registries of Sweden (SKAR), Australia (AOANJRR), and Kaiser Permanente (KPJRR). We included 1,072,924 TKA procedures for osteoarthritis. Factors studied included age, sex, ASA class, BMI category, prosthesis constraint, fixation, bearing mobility, patellar resurfacing, and polyethylene type. Cumulative percentage revision (CPR) was calculated using Kaplan-Meier estimates, and unadjusted Cox hazard ratios were used for comparisons. Random-effects generic inverse-variance meta-analytic methods were used to determine summary effects.

resultsWe found similarities in age and sex, but between-registry differences occurred in the other 7 factors studied. Patients from Sweden had lower BMI and ASA scores compared with other registries. Use of cement fixation was similar in the SKAR and KPJRR, but there were marked differences in patellar resurfacing and posterior stabilized component use. Meta-analysis results regarding survivorship favored patients aged ≥ 65 years and minimally stabilized components. There were inconsistent results with time for sex, fixation, and bearing mobility, and no differences for the patellar resurfacing or polyethylene type comparisons.

interpretationMarked practice variation was found. Use of minimally stabilized and possibly also cemented and fixed bearing prostheses is supported.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisHumansPolyethyleneProsthesis DesignProsthesis FailureRegistriesReoperationPolyethylene

Identifiers

PMID35113168
PMCPMC8808477

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.