ArticleTranslational vision science & technology2022
Clustered Volleys Stimulus Presentation for Multifocal Objective Perimetry.
Article in Translational vision science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Mapping simulated visual field defects with movie-viewing pupil perimetry.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Objective perimetry and diabetic retinopathy progression: a 10-year follow-up study.Frontiers in endocrinology · 2025Article
- The structure-function relationship between multifocal pupil perimetry and retinal nerve fibre layer in glaucoma.BMC ophthalmology · 2024Article
- The Trade-Off Between Luminance and Color Contrast Assessed With Pupil Responses.Translational vision science & technology · 2023Article
- Effects of Stimulus Luminance, Stimulus Color and Intra-Stimulus Color Contrast on Visual Field Mapping in Neurologically Impaired Adults Using Flicker Pupil Perimetry.Eye and brain · 2023Article
- Rapid, non-contact multifocal visual assessment in multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Discriminating early-stage diabetic retinopathy with subjective and objective perimetry.Frontiers in endocrinology · 2023Article
- Objective perimetry and progression of multiple sclerosis.eNeurologicalSci · 2022Article
- Comparison of unifocal, flicker, and multifocal pupil perimetry methods in healthy adults.Journal of vision · 2022Article
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10 authors.
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Abstract
purposeMultifocal pupillographic objective perimetry (mfPOP) is being developed as an alternative to subjective threshold perimetry for the management of visual and neurological disorders. Here, we evaluate, in normal subjects, differences in signal quality between the original mfPOP method of spatially sparse Continuous stimulus presentation and the new Clustered Volleys (CVs) method. We hypothesized that the CVs method would lead to increased signal-to-noise ratios (SNRs) over the original method due to the stabilization of gain within the pupillary system.
methodsData were collected from six separate studies where otherwise-identical pairs of mfPOP tests using either the original Continuous stimulus presentation method or the new CVs method were undertaken; 440 6-minute tests from 96 normal subjects of varying ages were included. Per-region SNRs were compared between the two methods.
resultsMean SNRs for the CVs mfPOP variants were between 35% and 57% larger than the original Continuous mfPOP variants (P < 0.001 in five of six studies). Similarly, the goodness-of-fit measure (r2) demonstrated large and significant fold increases of between 2.3× and 3.4× over the original method (all P < 0.001). Significant improvements in SNRs were present in all of the 88 test regions (44/eye), ranging between 8.4% and 93.7%; mean SNRs were significantly larger in 98% of test subjects.
conclusionsThe CVs mfPOP stimulus presentation method produced substantial increases in signal quality over the original method. This is likely due to the stabilization of pupillary gain during stimulus presentation. TRANSLATIONAL RELEVANCE: These improvements increase diagnostic accuracy and have enabled shorter, 80-second mfPOP tests to be developed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.