Evidence map›Paper›PMID 35112982›Full record

ArticleBioengineered2022

Pleckstrin homology-like domain family A, member 3, a miR-19a-3p-regulated gene, suppresses tumor growth in osteosarcoma by downregulating the Akt pathway.

Peng Wang, Yu Huang, Xin Xia, Jian Han, Lu Zhang, Wenzhi Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Heart failure with preserved ejection fraction in pigs causes shifts in posttranscriptional checkpoints.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  4. Role of SYT11 in human pan-cancer using comprehensive approaches.European journal of medical research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Peng WangDepartment of Orthopedics, The Second Affiliated Hospital, Dalian Medical University, Dalian, China.
Yu HuangDepartment of Orthopedics, The Second Affiliated Hospital, Dalian Medical University, Dalian, China.
Xin XiaDepartment of Orthopedics, The Second Affiliated Hospital, Dalian Medical University, Dalian, China.
Jian HanDepartment of Orthopedic Surgery, The Third People's Hospital of Dalian, Non-directly Affiliated Hospital of Dalian Medical University, Dalian, China.
Lu ZhangDepartment of Orthopedics, The Second Affiliated Hospital, Dalian Medical University, Dalian, China.
Wenzhi ZhaoDepartment of Orthopedics, The Second Affiliated Hospital, Dalian Medical University, Dalian, China.
Dalian Medical University · CNSecond Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleckstrin homology-like domain family A, member 3 (

Indexed as

Bone NeoplasmsOsteosarcomaCell Line, TumorComputational BiologyHumansMicroRNAsNuclear ProteinsProto-Oncogene Proteins c-aktSignal TransductionMicroRNAsMIRN19A microRNA, humanNuclear ProteinsProto-Oncogene Proteins c-aktTSSC3 proteinAkt/GSK3βbioinformatics analysismiR-19a-3posteosarcomaPHLDA3

Identifiers

PMID35112982
PMCPMC8974154
OpenAlexW4210431076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.