Evidence map›Paper›PMID 35112932›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022

Physiological dead space during exercise in patients with heart failure with preserved ejection fraction.

Bryce N Balmain, Andrew R Tomlinson, James P MacNamara, Satyam Sarma, Benjamin D Levine, Linda S Hynan, Tony G Babb

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Guideline
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  9. Ventilatory limitations in patients with HFpEF and obesity.Respiratory physiology & neurobiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bryce N BalmainInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas.ORCID 0000-0002-2642-7083
Andrew R TomlinsonInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas.
James P MacNamaraInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas.
Satyam SarmaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas.
Benjamin D LevineInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas.ORCID 0000-0001-9064-7251
Linda S HynanDepartment of Population and Data Sciences (Biostatistics) & Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas.
Tony G BabbInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas.ORCID 0000-0002-0515-2164
Presbyterian Hospital · USThe University of Texas Southwestern Medical Center · US

Funding

Targeting skeletal muscle to improve exercise capacity in heart failure with preserved ejection fraction.P01HL137630 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI LEVINE, BENJAMIN D · 2019 to 2023
$11.4M
American Heart Association-American Stroke AssociationNHLBI NIH HHS 1P01HL137630NHLBI NIH HHS P01 HL137630
6 · The paper itself

Abstract

Heart failure with preserved ejection fraction (HFpEF) is associated with cardiopulmonary abnormalities that may increase physiological dead space to tidal volume (VD/VT) during exercise. However, studies have not corrected VD/VT for apparatus mechanical dead space (VDM), which may confound the accurate calculation of VD/VT. We evaluated whether calculating physiological dead space with (VD/VT

Indexed as

Heart FailureAgedExerciseExercise TestHumansMiddle AgedPulmonary Gas ExchangeRespiratory Dead SpaceStroke VolumeTidal Volumedead spaceexercisegas exchange inefficiencyHFpEF

Identifiers

PMID35112932
PMCPMC8897014
OpenAlexW4210383714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.