Evidence map›Paper›PMID 35112928›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022

Critical closing pressure of the pharyngeal airway during routine drug-induced sleep endoscopy: feasibility and protocol.

Elahe Kazemeini, Eli Van de Perck, Marijke Dieltjens, Marc Willemen, Johan Verbraecken, Scott A Sands, Olivier M Vanderveken, Sara Op de Beeck

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07337239 (Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07337239 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy

TypeinterventionalSponsorUniversity Hospital, AntwerpRan2026 to 2027Enrolled21ConditionsObstructive Sleep ApneaArmsAdditional measurements during clinical standard follow-up drug-induced sleep endoscopy (DISE)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. [Dynamic assessment of upper airway in obstructive sleep apnea patients with a focus on drug-induced sleep endoscopy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Elahe KazemeiniTranslational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.ORCID 0000-0001-8700-6170
Eli Van de PerckTranslational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Marijke DieltjensTranslational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Marc WillemenMultidisciplinary Sleep Disorders Centre, Antwerp University Hospital, Edegem, Belgium.
Johan VerbraeckenLaboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
Scott A SandsDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Olivier M VandervekenENT, Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium.
Sara Op de BeeckTranslational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.ORCID 0000-0002-5978-9814
University of Antwerp · BEAntwerp University Hospital · BEBrigham and Women's Hospital · US

Funding

A Novel Pharmacological Therapy for Obstructive Sleep ApneaR01HL146697 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SANDS, SCOTT A · 2019 to 2023
$3.4M
American Heart Association (AHA) 15SDG25890059Fonds Wetenschappelijk Onderzoek (FWO) 1299822NFonds Wetenschappelijk Onderzoek (FWO) 12H4520NFonds Wetenschappelijk Onderzoek (FWO) 1833517NNHLBI NIH HHS R01 HL146697
6 · The paper itself

Abstract

In obstructive sleep apnea (OSA), there are various pathophysiological factors affecting the upper airway during sleep. Two prominent factors contributing to OSA are site and pattern of upper airway collapse and degree of pharyngeal collapsibility. In a clinical setting, drug-induced sleep endoscopy (DISE) is used to visualize the structures of the upper airway. Critical closing pressure (Pcrit) is the gold standard measure of pharyngeal collapsibility. This prospective clinical study aimed to investigate the feasibility and protocol of Pcrit measurements during DISE. Thirteen patients with OSA were included. Pcrit was calculated using peak inspiratory airflow and inspiratory ventilation. The proposed protocol was successful in Pcrit measurement during DISE in all subjects [median[Q1;Q3] Pcrit for "peak inspiratory method" (

Indexed as

PharynxSleep Apnea, ObstructiveEndoscopyFeasibility StudiesHumansPolysomnographyProspective StudiesReproducibility of ResultsSleepcollapsibilityDISEendotypingobstructive sleep apneaupper airway

Identifiers

PMID35112928
PMCPMC8993534
OpenAlexW4210350079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.