Evidence map›Paper›PMID 35112888›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2023

Long term safety and effectiveness of LVIS Jr for treatment of intracranial aneurysms- a Canadian Multicenter registry.

James McEachern, Daniela Iancu, Brian van Adel, Brian Drake, Zul Kaderali, Michael Spirou, Howard Lesiuk, Alain Weill, Daniel Roy, Jean Raymond and 2 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

James McEachernDepartment of Radiology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Daniela IancuDepartment of Radiology, 25443Centre hospitalier de'Universite de Montreal, Montreal, Canada.
Brian van AdelDivision of Neurology, 3710McMaster University, Hamilton, Canada.
Brian DrakeDivision of Neurosurgery, University of Ottawa, Ottawa, Canada.
Zul KaderaliDivision of Neurosurgery, University of Manitoba, Winnipeg, Canada.
Michael SpirouDepartment of Radiology, 25443Centre hospitalier de'Universite de Montreal, Montreal, Canada.
Howard LesiukDivision of Neurosurgery, University of Ottawa, Ottawa, Canada.
Alain WeillDepartment of Radiology, 25443Centre hospitalier de'Universite de Montreal, Montreal, Canada.
Daniel RoyDepartment of Radiology, 25443Centre hospitalier de'Universite de Montreal, Montreal, Canada.
Jean RaymondDepartment of Radiology, 25443Centre hospitalier de'Universite de Montreal, Montreal, Canada.
Isabel S HadziomerovicFaculty of Science, 5620McGill University, Montreal, Canada.
Jai ShankarDepartment of Radiology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.ORCID 0000-0002-3707-9723
Centre Hospitalier de l’Université de Montréal · CAUniversity of Manitoba · CAUniversity of Ottawa · CAMcGill University · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Low-profile Visible Intraluminal Support device (LVIS Jr) has become a commonly used intracranial stent for the treatment of intracranial aneurysms. However long-term stability and effectiveness remains to be seen. The purpose of the study was to assess the long-term efficacy, safety and durability of LVIS Jr. in a retrospective multicenter registry.

methodsPatients with saccular aneurysms treated at centers across Canada using LVIS Jr for intracranial aneurysms were included in this retrospective registry between the dates of January 2013 and April 2019. Self reported outcomes were collected and used to assess both perioperative and long term safety and effectiveness. Both univariate and multivariate analysis were performed.

resultsTotal of 196 patients (132 Women; mean age of 57.6 years) underwent endovascular aneurysm treatment with at least 1 LVIS Jr. stent. Mean aneurysm dome size was 7.4 mm, and mean neck size of 4.3 mm. Mean clinical and imaging follow up were 950 and 899 days respectively. Class I/II was achieved in 85% on long term follow up. Periprocedural morbidity and mortality was 4.6% and 2% and additional delayed morbidity and mortality was 3% and 2.5%. Aneurysm size >10 mm was independent predictor of periprocedural complication (OR 2.59,

conclusionThe LVIS Jr. intracranial stent is an effective device in the treatment of intracranial aneurysms. Satisfactory long term occlusion rates can be achieved safely with stent-assisted coil embolization.

Indexed as

Aortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationEmbolization, TherapeuticEndovascular ProceduresIntracranial AneurysmCanadaCerebral AngiographyFemaleHumansMiddle AgedRegistriesRetrospective StudiesStentsTreatment OutcomeefficacyIntracranial aneurysmsLVIS stent

Identifiers

PMID35112888
PMCPMC10152819
OpenAlexW4210538709

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.