Evidence map›Paper›PMID 35112559›Full record

ArticlePediatric endocrinology, diabetes, and metabolism2022

Assessment of the frequency of hormonal disorders of the gonads and bone mineral density among women treated for anorexia nervosa in adolescence.

Magdalena Wszolek, Karolina Ziora-Jakutowicz, Piotr Gorczyca, Katarzyna Rojewska, Katarzyna Ziora

Open access · diamondAbstract read
In one paragraph

Article in Pediatric endocrinology, diabetes, and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Does anorexia nervosa with adolescent onset need long-term follow-up?Pediatric endocrinology, diabetes, and metabolism · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Magdalena WszolekIndividual Specialist Medical Practice, Poland.
Karolina Ziora-JakutowiczDepartment of Genetics, Institute of Psychiatry and Neurology, Warsaw, Poland, Polska.
Piotr GorczycaDepartment of Psychiatry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Ka-towice, Poland.
Katarzyna RojewskaPediatric Endokcrinology, Public Clinical Hospital No.1 in Zabrze, Poland, Polska.
Katarzyna ZioraDepartment of Paediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Ka-towice, Poland.
Institute of Psychiatry and Neurology · PLKardio-Med Silesia · PLMedical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere are very few studies evaluating the activity of gonads in women treated for anorexia nervosa (AN) in adolescence, and reports on the bone mineral density in such patients are divergent. Objective Assessment of the incidence of gonadal hormonal function disorders and reduction of bone mineral density in women treated for AN in adolescence. MATERIAL AND

methodsOut of 97 women who had participated in a survey study, 56 reported personally to the clinic. Their somatic condition, body weight, and BMI were evaluated, as well as levels of oestradiol, LH, FSH in blood serum were determined and DEXA scans were performed.

resultsThe average period of hospitalisation until the time of the study was 7.08 ±4.47 years. BMI was as follows: 20.01 ±3.6 kg/m2. 25% women were still sick, 75% were considered cured. In 17.9% of the study subjects hypogonadotropic hy-pogonadism was diagnosed. Abnormal results of the densitometric scan were confirmed in 85.7% of the study subjects. In the group of women with normal body weight only 19% had normal levels of bone mineral density.

conclusions1. In almost 18% of women treated for AN in adolescence, disorders of the hormonal function of gonads persist, despite normal body weight in 50% of them. 2. Bone mineral density is reduced in most women treated for AN, which indicates the need to monitor the condition of the bones, an early introduction of prevention of osteopenia and osteoporosis since the onset of AN in order to prevent bone fractures in adulthood.

Indexed as

Anorexia NervosaBone Diseases, MetabolicOsteoporosisAdolescentAdultBone DensityFemaleGonadsHumansanorexia nervosabone densityhypogonadotrophic hypogonadism.long-term follow-up

Identifiers

PMID35112559
PMCPMC10226362
OpenAlexW4210338560

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.