Evidence map›Paper›PMID 35112321›Full record

ArticleFolia microbiologica2022

Evaluation of the antifungal activity of α, β, and δ-damascone and inclusion complexes in β-cyclodextrin against Candida spp.

Maria Rayane Correia de Oliveira, Maria Gabriely de Lima Silva, Antonia Thassya Lucas Dos Santos, Francisco Lucas Alves Batista, Roger Henrique Sousa da Costa, Anita Oliveira Brito Pereira Bezerra Martins, Beatriz Gonçalves da Cruz, Maria Flaviana Bezerra Morais-Braga, Henrique Douglas Melo Coutinho, Francisco Ernani Alves Magalhães and 3 more

Abstract read
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In one paragraph

Article in Folia microbiologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Maria Rayane Correia de OliveiraGraduate Program in Biotechnology-Northeast Biotechnology Network (RENORBIO), State University of Ceará (UECE), Av. Dr. Silas Munguba, 1700-Itaperi, Fortaleza, Ceará, 60741-000, Brazil.
Maria Gabriely de Lima SilvaLaboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Antonia Thassya Lucas Dos SantosLaboratory of Applied Mycology of Cariri, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Francisco Lucas Alves BatistaLaboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Roger Henrique Sousa da CostaLaboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Anita Oliveira Brito Pereira Bezerra MartinsLaboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Beatriz Gonçalves da CruzDepartment of Biological Chemistry, Regional University of Cariri, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Maria Flaviana Bezerra Morais-BragaLaboratory of Applied Mycology of Cariri, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Henrique Douglas Melo CoutinhoLaboratory of Microbiology and Molecular Biology, Department of Biological Chemistry, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil. hdmcoutinho@gmail.com.ORCID http://orcid.org/0000-0002-6634-4207
Francisco Ernani Alves MagalhãesLaboratory of Bioprospecting of Natural Products and Biotechnology (LBPNB), Center of Education, Sciences and Technology of the Inhamuns Region- CECITEC, State University of Ceará, Tauá, Ceará, CEP, 63660-000, Brazil.
Diniz Maciel de Sena JuniorDepartment of Biological Chemistry, Regional University of Cariri, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Alexandre Magno Rodrigues TeixeiraDepartment of Biological Chemistry, Regional University of Cariri, 63.100-000, Pimenta, Crato-Ceará, Brazil.
Irwin Rose Alencar de MenezesLaboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri-URCA, 63.100-000, Pimenta, Crato-Ceará, Brazil. irwin.alencar@urca.br.
Universidade Regional do Cariri · BRUniversidade Estadual do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the increase in fungal resistance to existing drugs, a need exists to search for new antifungals. This study aimed to evaluate the antifungal activity of α, β, and δ-damascone and inclusion complexes with β-cyclodextrin against different Candida spp. The inclusion complex of β-damascone was prepared by the co-evaporation method using three molar proportions (1:1; 2:1; 3:1 (βDA-βCD)) and analyzed using Fourier transform infrared spectroscopy (FTIR). Standard Candida albicans (CA INCQS 40,006), Candida krusei (CK INCQS 40,095), and Candida tropicalis (CT INCQS 40,042) strains were used to evaluate antifungal activity. The substances were tested individually or in association with fluconazole (FCZ). The IC

Indexed as

Antifungal Agentsbeta-CyclodextrinsCandidaFluconazoleMicrobial Sensitivity TestsNorisoprenoidsAntifungal Agentsbeta-CyclodextrinsFluconazoleNorisoprenoids

Identifiers

PMID35112321
OpenAlexW4210364659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.