Evidence map›Paper›PMID 35112320›Full record

ReviewAmerican journal of clinical dermatology2022

Leukonychia: What Can White Nails Tell Us?

Matilde Iorizzo, Michela Starace, Marcel C Pasch

Open access · hybridAbstract readReview
In one paragraph

Review in American journal of clinical dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. [Leukonychia following laser therapy for onychomycosis].Dermatologie (Heidelberg, Germany) · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Exposome Impact on Nail Health.Skin appendage disorders · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Matilde IorizzoPrivate Dermatology Practice, Bellinzona/Lugano, Switzerland.ORCID http://orcid.org/0000-0003-4227-5443
Michela StaraceDermatology Unit, IRCCS Policlinico Sant'Orsola, Department of Specialized, Experimental and Diagnostic Medicine, University of Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0002-3981-1527
Marcel C PaschDepartment of Dermatology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen (370), The Netherlands. marcel.pasch@radboudumc.nl.ORCID http://orcid.org/0000-0001-8169-9607
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in nail color can provide important clues of underlying systemic and skin disease. In particular, white discoloration (leukonychia) has a high prevalence with a wide array of potential relevant causes, from simple manicure habits to life-threatening liver or kidney failure. Therefore, a reliable assessment of the patient with leukonychia is essential. In the past, two classifications for leukonychia have been presented. The morphological classifies the nail according to the distribution of the white lines: total, partial, transversal, and longitudinal leukonychia. Mees' and Muehrcke's lines are examples of transversal leukonychia, while Terry's and Lindsay's nails are examples of total and partial leukonychia. The anatomical classifies according to the structure responsible for the white color: the nail plate in true leukonychia, the nail bed in apparent leukonychia, and the surface only in pseudoleukonychia. In this review, both morphological and anatomical features have been combined in an algorithm that enables clinicians to approach leukonychia efficiently and effectively.

Indexed as

Nail DiseasesNails, MalformedAlgorithmsHabitsHumansNails

Identifiers

PMID35112320
PMCPMC8809498
OpenAlexW4210322693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.