Evidence map›Paper›PMID 35112060›Full record

ArticleTurkish journal of surgery2021

Role of intra-abdominal pressure in the outcomes of perforation peritonitis: A prospective observational study.

N Pritesh Kumar, Lovenish Bains, Pawan Lal, Anurag Mishra, Mohd Yasir Beg, Haraesh Maranna

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Article in Turkish journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

N Pritesh KumarDepartment of Surgery, Maulana Azad Medical College, New Delhi, India.
Lovenish BainsDepartment of Surgery, Maulana Azad Medical College, New Delhi, India.
Pawan LalDepartment of Surgery, Maulana Azad Medical College, New Delhi, India.
Anurag MishraDepartment of Surgery, Maulana Azad Medical College, New Delhi, India.
Mohd Yasir BegDepartment of Surgery, Maulana Azad Medical College, New Delhi, India.
Haraesh MarannaDepartment of Surgery, Maulana Azad Medical College, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIntra-abdominal pressure (IAP) has been investigated for its role in causing morbidity and mortality, with various studies showing different degrees of correlation. There remains paucity of literature on this subject, applied to patients of perforation peritonitis, especially in the Indian subcontinent. MATERIAL AND

methodsIt is a prospective observational study involving 40 patients of perforation peritonitis undergoing exploratory laparotomy. IAP was measured as per WSACS (World Society of Abdominal Compartment Syndrome) guidelines. APACHE II (Acute Physiology And Chronic Health Evaluation- II) and SOFA (Sequential Organ Failure Assessment) were calculated. Data was collected regarding occurrence of prolonged ileus, burst abdomen, duration of hospital stay, 30 day mortality, and was statistically analyzed to correlate with IAP.

resultsAt admission, mean IAP was 13.37 mmHg, and the incidence of IAH was 65%. IAH was seen in 17.9% and 7.6% at 24 h and 48 h post-operatively. Incidence of prolonged ileus and burst abdomen were 7.7% and 22.5% respectively. Mortality rate was 17.5%. Mean duration of hospital stay was 13.45 days. Post-operative IAP correlated with mortality (p: 0.014) and post-operative SOFA score (p <0.05). Statistically significant correlation was also seen with the occurrence of prolonged ileus (p: 0.006). IAP did not significantly correlate with APACHE II score, occurrence of burst abdomen, and duration of hospital stay.

conclusionRise in IAP correlates with deterioration of SOFA score, and also with the occurrence of prolonged ileus. IAP is also a predictor of mortality. IAP measured post-operatively (24 and 48 hours) had a better correlation with these outcomes than the value measured at admission. No statistically significant correlation of IAP with the occurrence of burst abdomen and duration of hospital stay could be found, which warrants further studies with a larger population.

Indexed as

abdominal compartment syndromeintra-abdominal hypertensionintra-abdominal pressurePerforation peritonitis

Identifiers

PMID35112060
PMCPMC8776416

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