Evidence map›Paper›PMID 35111961›Full record

ArticleGE Portuguese journal of gastroenterology2022

Variation in the Care of Acute Liver Failure: A Survey of Intensive Care Professionals.

Filipe S Cardoso, Mark J Mcphail, Constantine J Karvellas, Valentin Fuhrmann, Nuno Germano, Georg Auzinger

Open access · diamondAbstract read
In one paragraph

Article in GE Portuguese journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Filipe S CardosoIntensive Care Unit, Curry Cabral Hospital, Lisbon, Portugal.
Mark J McphailLiver Intensive Therapy Unit, King's College Hospital, London, United Kingdom.
Constantine J KarvellasDepartment of Critical Care Medicine, University of Alberta, Edmonton, Alberta, Canada.
Valentin FuhrmannDepartment of Medicine B, Gastroenterology and Hepatology, University of Münster, Münster, Germany.
Nuno GermanoIntensive Care Unit, Curry Cabral Hospital, Lisbon, Portugal.
Georg AuzingerLiver Intensive Therapy Unit, King's College Hospital, London, United Kingdom.
Hospital Curry Cabral · PTKing's College Hospital · GBUniversity of Alberta · CAUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute liver failure (ALF) is a rare disease with potentially high mortality. We sought to assess the individual approach to ALF by intensive care unit (ICU) professionals.

methodsCross-sectional survey of ICU professionals. Web-based survey capturing data on respondents' demographics, characteristics of patients with ALF admitted to ICU, and their management.

resultsAmong 204 participants from 50 countries, 140 (68.6%) worked in Europe, 146 (71.6%) were intensivists, 142 (69.6%) admitted <25 patients with ALF per year, and 166 (81.8%) reported <25% of patients had paracetamol-related ALF. On patients' outcomes, 126 (75.0%) reported an emergency liver transplantation (ELT) rate <25% and 140 (73.3%) a hospital mortality rate <50%. The approach to ALF in the ICU varied with age, region, level of training, type of hospital, and etiology (prescribing N-acetylcysteine for paracetamol toxicity, triggers for endotracheal intubation, measurement of and strategies for lowering serum ammonia, extracorporeal device deployment, and prophylactic antibiotics).

conclusionsThe management of patients with ALF by ICU professionals differed substantially concerning the relevant clinical measures taken. Further education and high-quality research are warranted.

Indexed as

Critical careHepatitisOutcomesSurvey

Identifiers

PMID35111961
PMCPMC8787500
OpenAlexW3165607898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.