Evidence map›Paper›PMID 35111960›Full record

ArticleGE Portuguese journal of gastroenterology2022

Phenotype-Genotype Correlation in Colorectal Cancer: A Real-Life Study.

Catarina Frias-Gomes, Ana Carla Sousa, Inês Rolim, Ana Raquel Henriques, Francisco Branco, André Janeiro, Sara Malveiro, Ana Rita Dário, Maria Helena Oliveira, Paula Borralho and 5 more

Open access · diamondAbstract read
In one paragraph

Article in GE Portuguese journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Catarina Frias-GomesServiço de Gastrenterologia, Departamento de Cirurgia, Hospital Beatriz Ângelo, Loures, Portugal.
Ana Carla SousaGenomed, Instituto de Medicina Molecular, Lisboa, Portugal.
Inês RolimServiço de Anatomia Patológica, Instituto Português de Oncologia Francisco Gentil, Lisboa, Portugal.
Ana Raquel HenriquesInstituto de Anatomia Patológica, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Francisco BrancoServiço de Oncologia Médica, Departamento de Oncologia, Hospital Beatriz Ângelo, Loures, Portugal.
André JaneiroGenomed, Instituto de Medicina Molecular, Lisboa, Portugal.
Sara MalveiroGenomed, Instituto de Medicina Molecular, Lisboa, Portugal.
Ana Rita DárioGenomed, Instituto de Medicina Molecular, Lisboa, Portugal.
Maria Helena OliveiraServiço de Anatomia Patológica, Hospital Beatriz Ângelo, Loures, Portugal.
Paula BorralhoInstituto de Anatomia Patológica, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
José Alberto TeixeiraServiço de Oncologia Médica, Departamento de Oncologia, Hospital Beatriz Ângelo, Loures, Portugal.
Ana FariaServiço de Oncologia Médica, Departamento de Oncologia, Hospital Beatriz Ângelo, Loures, Portugal.
Rui MaioServiço de Cirurgia Geral, Departamento de Cirurgia, Hospital Beatriz Ângelo, Loures, Portugal.
Isabel FonsecaServiço de Anatomia Patológica, Instituto Português de Oncologia Francisco Gentil, Lisboa, Portugal.
Marília CravoServiço de Gastrenterologia, Departamento de Cirurgia, Hospital Beatriz Ângelo, Loures, Portugal.
Hospital Beatriz Ângelo · PTInstituto de Medicina Molecular João Lobo AntunesUniversity of Lisbon · PTHospital CUF DescobertasInstituto Português de Oncologia Francisco Gentil · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsColorectal cancer (CRC) is a heterogeneous disease with distinctive genetic pathways, such as chromosomal instability, microsatellite instability and methylator pathway. Our aim was to correlate clinical and genetic characteristics of CRC patients in order to understand clinical implications of tumour genotype.

methodsSingle-institution retrospective cohort of patients who underwent curative surgery for CRC, from 2012 to 2014.

resultsOverall, 242 patients were included (males 57.4%, age 69.3 ± 12.9 years; median follow-up 49 months).

conclusionIn our cohort,

Indexed as

BRAFDisease-free survivalMismatch repairOverall survivalRASTumour heterogeneity

Identifiers

PMID35111960
PMCPMC8787526
OpenAlexW3166683416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.