Evidence map›Paper›PMID 35111873›Full record

ArticleOpen forum infectious diseases2022

Association Between Foot Surgery Type and Subsequent Healing in Veterans With Moderate-to-Severe Diabetic Foot Infections.

Justin J Kim, Alyson J Littman, John D Sorkin, Mary-Claire Roghmann

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Justin J KimGeriatrics Research Education and Clinical Center, Veterans Affairs Maryland Health Care System, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-6544-6797
Alyson J LittmanSeattle Epidemiologic Research and Information Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-4247-8286
John D SorkinGeriatrics Research Education and Clinical Center, Veterans Affairs Maryland Health Care System, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-2496-0965
Mary-Claire RoghmannGeriatrics Research Education and Clinical Center, Veterans Affairs Maryland Health Care System, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-1063-9257
University of Maryland, Baltimore · USUniversity of Puget Sound · USVA Maryland Health Care System · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Preventing Diabetic Foot Ulcers through Manipulating the Skin MicrobiotaI01CX001601 · VA · BALTIMORE VA MEDICAL CENTER · PI ROGHMANN, MARY-CLAIRE · 2018 to 2023
–
CSRD VA I01 CX001601NIA NIH HHS P30 AG028747
6 · The paper itself

Abstract

backgroundDiabetic foot infections are a common precursor to lower extremity amputations. The treatment of diabetic foot infections involves both medical and surgical management, of which limb-sparing surgeries are increasingly preferred over amputations at or above the ankle to preserve mobility and quality of life. The outcomes following these limb-sparing surgeries are not well described.

methodsThis was a single-center, retrospective cohort study of 90 Veterans with moderate-to-severe diabetic foot infections between 2017 and 2019 from the Veterans Affairs Maryland Health Care System. The exposure was foot surgery with bone resection (ie, toe amputation, metatarsal resection, transmetatarsal amputation) vs debridement alone. The outcome was healing within 1 year. We used log-binomial regression to assess the association between foot surgery type and healing, stratify by infection location, and evaluate potential confounding variables.

resultsThe cumulative incidence of healing after foot surgery with bone resection was greater than that following debridement (risk ratio [RR], 1.80 [95% confidence interval {CI}, 1.17-2.77]). This association was modified by infection location and greater for toe infections (RR, 4.52 [95% CI, 1.30-15.7]) than other foot infections (RR, 1.19 [95% CI, .69-2.02]). We found no evidence of confounding by comorbidities or infection severity.

conclusionsFor patients with toe infections, foot surgery with bone resection was associated with better healing than debridement alone. The multiple specialties caring for patients with diabetic foot infections need a stronger common knowledge base-from studies like this and future studies-to better counsel patients about their treatment and prognosis.

Indexed as

amputationdebridementdiabetic foot infectionretrospective cohort studysurgery

Identifiers

PMID35111873
PMCPMC8802798
OpenAlexW4200217286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.