Evidence map›Paper›PMID 35111798›Full record

ArticleFrontiers in nutrition2021

Effects and Reversibility of Pre- and Post-natal Iron and Omega-3 Fatty Acid Deficiency, Alone and in Combination, on Bone Development in Rats.

Estelle Strydom, Lizelle Zandberg, Erna T Kemp, Philip vZ Venter, Cornelius M Smuts, Herculina S Kruger, Jeannine Baumgartner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Estelle StrydomCentre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa.
Lizelle ZandbergCentre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa.
Erna T KempCentre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa.
Philip vZ VenterSchool of Mechanical and Nuclear Engineering, North-West University, Potchefstroom, South Africa.
Cornelius M SmutsCentre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa.
Herculina S KrugerCentre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa.
Jeannine BaumgartnerCentre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa.
North-West University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both iron and omega-3 (n-3) polyunsaturated fatty acids may play an important role in bone development. The aim of this study was to investigate the effects of pre- and post-natal iron and n-3 fatty acid deficiency (FAD), alone and in combination, on bone development in rats, and to determine whether effects are reversible when a sufficient diet is provided post-weaning. Using a 2×2-factorial design, 56 female Wistar rats were allocated to one of four diets: (1) control, (2) iron deficient (ID), (3) n-3 FAD or (4) ID and n-3 FAD, and were maintained on the respective diets throughout gestation and lactation. At weaning (post-natal day [PND] 21), offspring (

Indexed as

bone developmentbone mineral densitybone strengthironomega-3 polyunsaturated fatty acid (n-3 PUFA)

Identifiers

PMID35111798
PMCPMC8801778
OpenAlexW4205650251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.