Evidence map›Paper›PMID 35111729›Full record

ArticleFrontiers in chemistry2021

New Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization.

Ponnusamy Packialakshmi, Perumal Gobinath, Daoud Ali, Saud Alarifi, Raman Gurusamy, Akbar Idhayadhulla, Radhakrishnan Surendrakumar

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ponnusamy PackialakshmiResearch, Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanampatti, India.
Perumal GobinathResearch, Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanampatti, India.
Daoud AliDepartment of Zoology, College of Science, King Saud University (KSU), Riyadh, Saudi Arabia.
Saud AlarifiDepartment of Zoology, College of Science, King Saud University (KSU), Riyadh, Saudi Arabia.
Raman GurusamyDepartment of Life Sciences, Yeungnam University, Gyeongsan, South Korea.
Akbar IdhayadhullaResearch, Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanampatti, India.
Radhakrishnan SurendrakumarResearch, Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanampatti, India.
Bharathidasan University · INKing Saud University · SAYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we synthesize the sulfonated Schiff bases of the chitosan derivatives 2a-2j without the use of a catalyst in two moderately straightforward steps with good yield within a short reaction time. The morphology and chemical structure of chitosan derivatives were investigated using FT-IR, NMR (

Indexed as

anticancer activityin-silico molecular dockingMCF-7schiff baseSEMstructure activity relationship

Identifiers

PMID35111729
PMCPMC8801607
OpenAlexW4206677285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.