Evidence map›Paper›PMID 35111691›Full record

ArticleFrontiers in cellular and infection microbiology2021

Association Between Vaginal

Yingxuan Zhang, Si Chen, Xiaofeng Chen, Huimin Zhang, Xuge Huang, Xiaomeng Xue, Yinan Guo, Xiaofeng Ruan, Xiaorong Liu, Gaopi Deng and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Inflammatory landscape ofFrontiers in immunology · 2026
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  2. iScience · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yingxuan ZhangThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Si ChenThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiaofeng ChenThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Huimin ZhangThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xuge HuangThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiaomeng XueThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yinan GuoThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiaofeng RuanThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiaorong LiuThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Gaopi DengDepartment of Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese, Guangzhou, China.
Songping LuoDepartment of Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese, Guangzhou, China.
Jie GaoDepartment of Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese, Guangzhou, China.
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The early diagnosis and treatment of ectopic pregnancy (EP) remains a major challenge. Despite a known link between vaginal microbiota and female reproductive health, few studies have focused on the association between vaginal microbiota and pregnancy location. This nested case-control study aimed to characterize the vaginal microbiota in tubal pregnancy (TP) among symptomatic women in early pregnancy. Women with symptomatic early pregnancy of unknown location (PUL) were included in this study. 16S rDNA gene sequencing was performed to assess vaginal microbial diversity and relative abundance. Machine learning and multivariate logistic regression were also used to evaluate the association between

Indexed as

Pregnancy, TubalVaginaCase-Control StudiesFemaleGardnerellaHumansPregnancyRNA, Ribosomal, 16SRNA, Ribosomal, 16SChinaGardnerellasymptomatic early pregnancytubal pregnancyvaginal microbiota

Identifiers

PMID35111691
PMCPMC8801712
OpenAlexW4206634189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.