Evidence map›Paper›PMID 35111674›Full record

ArticleFrontiers in oncology2021

Mutations in

Alexandra Butzmann, Kaushik Sridhar, Diwash Jangam, Hanbing Song, Amol Singh, Jyoti Kumar, Karen M Chisholm, Benjamin Pinsky, Franklin Huang, Robert S Ohgami

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Analysis of Notch1 protein expression in methotrexate-associated lymphoproliferative disorders.Journal of clinical and experimental hematopathology : JCEH · 2024
    Article
  4. Article
  5. EBV-Related Lymphoproliferative Diseases: A Review in Light of New Classifications.Mediterranean journal of hematology and infectious diseases · 2024
    Review
  6. Review
  7. New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.Virchows Archiv : an international journal of pathology · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Alexandra ButzmannAgilent Technologies, Santa Clara, CA, United States.
Kaushik SridharDepartment of Pathology, University of California, San Francisco, San Francisco, CA, United States.
Diwash JangamDepartment of Pathology, Stanford University, Stanford, CA, United States.
Hanbing SongDepartment of Pathology, University of California, San Francisco, San Francisco, CA, United States.
Amol SinghDepartment of Pathology, Stanford University, Stanford, CA, United States.
Jyoti KumarDepartment of Pathology, Stanford University, Stanford, CA, United States.
Karen M ChisholmDepartment of Laboratories, Seattle Children's Hospital, Seattle, WA, United States.
Benjamin PinskyDepartment of Pathology, Stanford University, Stanford, CA, United States.
Franklin HuangDepartment of Pathology, University of California, San Francisco, San Francisco, CA, United States.
Robert S OhgamiDepartment of Pathology, University of California, San Francisco, San Francisco, CA, United States.
Stanford University · USUniversity of California, San Francisco · USAgilent Technologies (United States) · USSeattle Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transplant lymphoproliferative disorders (PTLD) are diseases occurring in immunocompromised patients after hematopoietic stem cell transplantation (HCT) or solid organ transplantation (SOT). Although PTLD occurs rarely, it may be associated with poor outcomes. In most cases, PTLD is driven by Epstein-Barr virus (EBV) infection. Few studies have investigated the mutational landscape and gene expression profile of PTLD. In our study, we performed targeted deep sequencing and RNA-sequencing (RNA-Seq) on 16 cases of florid follicular hyperplasia (FFH) type PTLD and 15 cases of other PTLD types that include: ten monomorphic (M-PTLD), three polymorphic (P-PTLD), and two classic Hodgkin lymphoma type PTLDs (CHL-PTLD). Our study identified recurrent mutations in

Indexed as

Epstein-Barr Virus (EBV)florid follicular hyperplasianext generation (deep) sequencing (NGS)PTLDtargeted sequencingwhole transcriptome sequencing

Identifiers

PMID35111674
PMCPMC8801788
OpenAlexW4205638956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.