Evidence map›Paper›PMID 35111578›Full record

ReviewWorld journal of psychiatry2022

Resilience to the effects of social stress on vulnerability to developing drug addiction.

Claudia Calpe-López, Maria A Martínez-Caballero, Maria P García-Pardo, Maria A Aguilar

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Examining Resilience in Those With and Without Suicidal Ideation.Behavioral sciences (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Toward a solution-focused addiction science.Frontiers in public health · 2025
    Article
  10. Why do people use drugs? A neglected question.Irish journal of medical science · 2024
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Claudia Calpe-LópezDepartment of Psychobiology, University of Valencia, Valencia 46010, Spain.
Maria A Martínez-CaballeroDepartment of Psychobiology, University of Valencia, Valencia 46010, Spain.
Maria P García-PardoFaculty of Social and Human Sciences, University of Zaragoza, Teruel 44003, Spain.
Maria A AguilarDepartment of Psychobiology, University of Valencia, Valencia 46010, Spain. asuncion.aguilar@uv.es.
Universidad de Zaragoza · ESCreative Research Enterprises (United States) · USJackson and Tull (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We review the still scarce but growing literature on resilience to the effects of social stress on the rewarding properties of drugs of abuse. We define the concept of resilience and how it is applied to the field of drug addiction research. We also describe the internal and external protective factors associated with resilience, such as individual behavioral traits and social support. We then explain the physiological response to stress and how it is modulated by resilience factors. In the subsequent section, we describe the animal models commonly used in the study of resilience to social stress, and we focus on the effects of chronic social defeat (SD), a kind of stress induced by repeated experience of defeat in an agonistic encounter, on different animal behaviors (depression- and anxiety-like behavior, cognitive impairment and addiction-like symptoms). We then summarize the current knowledge on the neurobiological substrates of resilience derived from studies of resilience to the effects of chronic SD stress on depression- and anxiety-related behaviors in rodents. Finally, we focus on the limited studies carried out to explore resilience to the effects of SD stress on the rewarding properties of drugs of abuse, describing the current state of knowledge and suggesting future research directions.

Indexed as

Animal modelsDepressionDrug addictionResilienceSocial defeatStress

Identifiers

PMID35111578
PMCPMC8783163
OpenAlexW4206002378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.