Evidence map›Paper›PMID 35111516›Full record

ArticleFujita medical journal2020

Evaluation of perinatal autonomic development in infants using the QT/RR variability ratio.

Yuri Mizutani, Arisa Kojima, Yuka Takeuchi, Hirofumi Kusuki, Keiko Sugimoto, Keisuke Osakabe, Naohiro Ichino, Masayuki Fujino, Kazuyoshi Saito, Masafumi Miyata and 2 more

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In one paragraph

Article in Fujita medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yuri MizutaniGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Arisa KojimaDepartment of Pediatrics, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Yuka TakeuchiGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Hirofumi KusukiGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Keiko SugimotoGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Keisuke OsakabeGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Naohiro IchinoGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Masayuki FujinoDepartment of Joint Research Laboratory of Clinical Medicine, Fujita Health University Hospital, Toyoake, Aichi, Japan.
Kazuyoshi SaitoDepartment of Joint Research Laboratory of Clinical Medicine, Fujita Health University Hospital, Toyoake, Aichi, Japan.
Masafumi MiyataDepartment of Joint Research Laboratory of Clinical Medicine, Fujita Health University Hospital, Toyoake, Aichi, Japan.
Tsuneaki SadanagaSeigato Hospital, Kumamoto, Kumamoto, Japan.
Tadayoshi HataGraduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Fujita Health University · JPFujita Health University Hospital · JPKumamoto University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDevelopment of the autonomic nervous system may play a role in myocardial repolarization lability in infants, but its relationship to repolarization abnormalities remains unclear. Thus, the aim of the present study was to evaluate the relationship between gestational age and ventricular repolarization lability using the variability ratio (VR).

methodsInfants who underwent electrocardiography at a 1-month check-up were included (n=209; 125 males). Gestational age and the following four VR parameters at 1 month of age were compared: VR-I, SDQT/SDRR; VR-II, SDQT/rMSSD; VR-III, SDQTc/SDRR; and VR-IV, SDQTc/rMSSD; where SD, QTc, and rMSSD are standard deviation, QT interval corrected using Fridericia's formula, and root mean square difference of successive RR intervals, respectively. Twenty-eight preterm infants born at <37 weeks of gestation and 181 full-term infants were included.

resultsSignificant correlations were observed between gestational age and VR-I, -III, and -IV (all p<0.05). All VR values were significantly higher in preterm infants compared with full-term infants (I: 0.54 vs 0.48, II: 1.15 vs 0.96, III: 0.88 vs 0.68, IV: 1.59 vs 1.39; median, all p<0.05).

conclusionVR assessed at 1 month after birth was impaired in preterm infants, suggesting immaturity of their cardiac autonomic nervous system and ventricular myocardial repolarization.

Indexed as

Gestational ageHeart rate variabilityMyocardial repolarizationVariability ratio

Identifiers

PMID35111516
PMCPMC8766653
OpenAlexW3083995879

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.