ArticleCureus2021
Cystoid Macular Edema Associated With Venous Stasis in a Patient With Previously Undiagnosed Hyperhomocysteinemia.
Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Nutritional Factors: Benefits in Glaucoma and Ophthalmologic Pathologies.Life (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 74-year-old female patient visited our department reporting unilateral painless vision reduction in her left eye noticed a few months ago. Clinical examination revealed decreased visual acuity in the left eye. Fundoscopy showed bilateral retinal venous stasis with cystoid macular edema in the affected eye, also confirmed by optical coherence tomography (OCT) imaging. OCT angiography showed no evidence of ischemia. Bilateral findings raised suspicion for a systemic underlying cause. Laboratory tests showed elevated homocysteine plasma levels. Brain MRI showed ischemic encephalopathy. Hyperhomocysteinemia creates a hypercoagulable state and therefore it is a risk factor for vascular thrombosis and retinal vein occlusion. Our patient was considered to suffer from an impending retinal vein occlusion due to venous stasis, causing a persistent macular edema, and, therefore, was treated with anti-vascular endothelial growth factor (VEGF) injections. She was also prescribed oral folic acid for life. Her visual acuity showed improvement and remained stable for a long period of time. When macular edema reoccurred she was treated with another intravitreal injection.
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Registered trials
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