Evidence map›Paper›PMID 35111412›Full record

ArticlePeerJ2022

Functional genetic variants in complement component 7 confer susceptibility to gastric cancer.

Siyue Wang, Wenqian Hu, Yuning Xie, Hongjiao Wu, Zhenxian Jia, Zhi Zhang, Xuemei Zhang

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Siyue WangSchool of Public Health, North China University of Science and Technology, Tangshan, China.
Wenqian HuSchool of Public Health, North China University of Science and Technology, Tangshan, China.
Yuning XieSchool of Public Health, North China University of Science and Technology, Tangshan, China.
Hongjiao WuSchool of Public Health, North China University of Science and Technology, Tangshan, China.
Zhenxian JiaSchool of Public Health, North China University of Science and Technology, Tangshan, China.
Zhi ZhangAffiliated Tangshan Gongren Hospital, North China University of Science and Technology, Tangshan, China.
Xuemei ZhangSchool of Public Health, North China University of Science and Technology, Tangshan, China.
North China University of Science and Technology · CNTangshan Gongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComplement system plays an important role in innate immunity which involved in the changes tumor immune microenvironment by mediating the inflammatory response. This study aims to explore the relationship between complement component 7 ( MATERIALS AND

methodsAll selected SNPs of

resultsUnconditional logistic regression showed that individuals with

conclusionsThese findings highlight the role of

Indexed as

MicroRNAsStomach NeoplasmsComplement C7FemaleGenetic Predisposition to DiseaseGenotypeHumansMaleRisk FactorsTumor MicroenvironmentComplement C7MicroRNAsMIRN591 microRNA, humanC7Gastric cancerGenetic variantSingle nucleotide polymorphism

Identifiers

PMID35111412
PMCPMC8781313
OpenAlexW4205270598

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.