Evidence map›Paper›PMID 35111366›Full record

ReviewAging and disease2022

Protective Effects of Exercise Become Especially Important for the Aging Immune System in The Covid-19 Era.

Katarzyna Domaszewska, Michał Boraczyński, Yi-Yuan Tang, Joanna Gronek, Krystian Wochna, Tomasz Boraczyński, Dariusz Wieliński, Piotr Gronek

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Aging and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06568393 (The Effect of Calisthenic Exercises on Quality of Life in Post-Covid Syndrome), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06568393 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Calisthenic Exercises on Quality of Life in Post-Covid Syndrome: A Randomized Controlled Trial

TypeinterventionalSponsorBahçeşehir UniversityRan2023 to 2024Enrolled176ConditionsQuality of LifeArmsCalisthenic exercise
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Promoting Physical Activity and Health in the Workplace: A Qualitative Study among University Workers, Spain.International journal of environmental research and public health · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Katarzyna Domaszewska1Department of Physiology and Biochemistry, Poznan University of Physical Education, Poland.
Michał Boraczyński2Faculty of Health Sciences, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland.
Yi-Yuan Tang3College of Health Solutions, Arizona State University, USA.
Joanna Gronek4Laboratory of Genetics, Department of Dance and Gymnastics, Poznan University of Physical Education, Poland.
Krystian Wochna5Laboratory of Swimming and Water Lifesaving, Faculty of Sport Sciences, Poznan University of Physical Education, Poland.
Tomasz Boraczyński6Faculty of Health Sciences, Olsztyn University, Poland.
Dariusz Wieliński7Department of Anthropology and Biometry, Poznan University of Physical Education, Poland.
Piotr Gronek4Laboratory of Genetics, Department of Dance and Gymnastics, Poznan University of Physical Education, Poland.
Hungarian University of Sports Science · HUUniversity School of Physical Education in Kraków · PLIntercollege · CYUniversity of Computer Sciences and Economics in Olsztyn · PLUniversity of Life Sciences in Lublin · PLUniversity of Warmia and Mazury in Olsztyn · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is a complex, multietiological process and a major risk factor for most non-genetic, chronic diseases including geriatric syndromes that negatively affect healthspan and longevity. In the scenario of "healthy or good aging", especially during the COVID-19 era, the proper implementation of exercise as "adjuvant" or "polypill" to improve disease-related symptoms and comorbidities in the general population is a top priority. However, there is still a gap concerning studies analyzing influence of exercise training to immune system in older people. Therefore, the aim of this review is to provide a brief summary of well-established findings in exercise immunology and immunogerontology, but with a focus on the main exercise-induced mechanisms associated with aging of the immune system (immunosenescence). The scientific data strongly supports the notion that regular exercise as a low-cost and non-pharmacological treatment approach, when adjusted on an individual basis in elderly, induce multiple rejuvenating mechanisms: (1) affects the telomere-length dynamics (a "telo-protective" effect), (2) promote short- and long-term anti-inflammatory effects (via e.g., triggering the anti-inflammatory phenotype), 3) stimulates the adaptive immune system (e.g., helps to offset diminished adaptive responses) and in parallel inhibits the accelerated immunosenescence process, (4) increases post-vaccination immune responses, and (5) possibly extends both healthspan and lifespan.

Indexed as

aging processCOVID-19exerciseimmune systemimmunosenescence

Identifiers

PMID35111366
PMCPMC8782560
OpenAlexW4207044608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.