Trial reportNeural plasticity2022
The Effect of Virtual Reality on Motor Anticipation and Hand Function in Patients with Subacute Stroke: A Randomized Trial on Movement-Related Potential.
Trial report in Neural plasticity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Pooled it
- Comparative efficacy of virtual reality interventions with varying immersion levels on upper limb motor function, hand dexterity, and independence in the daily life of stroke survivors: a systematic review and network meta-analysis.Frontiers in neurology · 2026Pooled it
- Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2025Pooled it
- Virtual Reality Enhanced Exercise Training in Upper Limb Function of Patients With Stroke: Meta-Analytic Study.Journal of medical Internet research · 2025Pooled it
- Pooled it
- The efficacy of virtual reality for upper limb rehabilitation in stroke patients: a systematic review and meta-analysis.BMC medical informatics and decision making · 2024Pooled it
- Effect of different modalities of artificial intelligence rehabilitation techniques on patients with upper limb dysfunction after stroke-A network meta-analysis of randomized controlled trials.Frontiers in neurology · 2023Pooled it
- The Effect of Virtual Reality on Motor Anticipation and Hand Function in Patients with Subacute Stroke: A Randomized Trial on Movement-Related Potential.Neural plasticity · 2022Trial
- Virtual Reality-Assisted Rehabilitation for Upper-Limb Function in Stroke Survivors: A Systematic Review.Brain sciences · 2026Review
- Immersive Virtual Reality for Stroke Rehabilitation: Linking Clinical and Digital Measures of Motor Recovery-A Pilot Study.Bioengineering (Basel, Switzerland) · 2026Article
- Evaluating the Effectiveness of Immersive Virtual Reality Rehabilitation Games With Enhanced Visual Training for Hand Motor Function Improvement Using Electromyography: Randomized Controlled Trial.JMIR serious games · 2025Article
- Upper extremity motor improvement after carotid endarterectomy associated with postoperative recovery in cerebral perfusion and cortical neurotransmitter receptor function.Neurosurgical review · 2025Article
- Assessing Motor Cortical Activity: How Repetitions Impact Motor Execution and Imagery Analysis.Psychophysiology · 2025Article
- Virtual Reality: A New Frontier of Physical Rehabilitation.Sensors (Basel, Switzerland) · 2025Review
- Effects of tactile feedback in post-stroke hand rehabilitation on functional connectivity and cortical activation: an fNIRS study.Biomedical optics express · 2025Article
- Effectiveness of virtual reality-supported exercise therapy in improving upper extremity function and activities of daily living among patients after stroke: a systematic review of randomized control trials.Osong public health and research perspectives · 2024Article
- Effect of the VR-guided grasping task on the brain functional network.Biomedical optics express · 2024Article
- Age-related decline of online visuomotor adaptation: a combined effect of deteriorations of motor anticipation and execution.Frontiers in aging neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Impaired cognitive ability to anticipate the required control for an upcoming task in patients with stroke may affect rehabilitation outcome. The cortical excitability of task-related motor anticipation for upper limb movement induced by virtual reality (VR) training remains unclear. Aims: To investigate the effect of VR training on the cortical excitability of motor anticipation when executing upper limb movement in patients with subacute stroke. Methods: A total of thirty-six stroke survivors with upper limb hemiparesis resulting from the first occurrence of stroke within 1 to 3 months were recruited. Participants were randomly allocated to the VR intervention group or conventional therapy group. Event-related potentials (ERPs) and electromyography (EMG) were used to simultaneously record the cortical excitability and muscle activities during palmar grasp motion. Outcome measures of the contingent negative variation (CNV) latency and amplitude, EMG reaction time, Upper Limb Fugl-Meyer Assessment (UL-FMA), Action Research Arm Test (ARAT), and National Institutes of Health Stroke Scale (NIHSS) were recorded pre- and postintervention. The between-group difference was analysed by mixed model ANOVA. Results: The EMG onset time of the paretic hand in the VR group was earlier than that observed in the control group ( Conclusions: VR intervention is superior to conventional therapy to improve the cognitive neural process of motor anticipation and reduce the excessive compensatory activation of the contralesional hemisphere. The improvements observed in the cognitive neural process corroborated with the improvements in hand function.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.