Evidence map›Paper›PMID 35111160›Full record

ArticleFrontiers in immunology2021

Metabolic Enzyme Triosephosphate Isomerase 1 and Nicotinamide Phosphoribosyltransferase, Two Independent Inflammatory Indicators in Rheumatoid Arthritis: Evidences From Collagen-Induced Arthritis and Clinical Samples.

Ming Lei, Meng-Qing Tao, Yi-Jin Wu, Liang Xu, Zhe Yang, Yan Li, Opeyemi Joshua Olatunji, Xiao-Wan Wang, Jian Zuo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

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  10. Resveratrol-induced SIRT1 activation inhibits glycolysis-fueled angiogenesis under rheumatoid arthritis conditions independent of HIF-1α.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ming LeiXin'an Medicine Research Center, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
Meng-Qing TaoXin'an Medicine Research Center, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
Yi-Jin WuXin'an Medicine Research Center, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
Liang XuDepartment of Rheumatology, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
Zhe YangDepartment of Traditional Chinese Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
Yan LiXin'an Medicine Research Center, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
Opeyemi Joshua OlatunjiFaculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Thailand.
Xiao-Wan WangDepartment of Rheumatology, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
Jian ZuoXin'an Medicine Research Center, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, China.
First Affiliated Hospital of Wannan Medical College · CNWannan Medical College · CNPrince of Songkla University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic intervention is a novel anti-rheumatic approach. The glycolytic regulator NAMPT has been identified as a therapeutic target of rheumatoid arthritis (RA), while other metabolic regulators coordinating NAMPT to perpetuate inflammation are yet to be investigated. We continuously monitored and validated expression changes of

Indexed as

BiomarkersAnimalsArthritis, ExperimentalArthritis, RheumatoidComputational BiologyCytokinesDisease Models, AnimalDisease SusceptibilityGene ExpressionGene Expression ProfilingHumansHypoxia-Inducible Factor 1, alpha SubunitInflammation MediatorsMacrophage ActivationMacrophagesNicotinamide PhosphoribosyltransferaseBiomarkersCytokinesHif1a protein, ratHypoxia-Inducible Factor 1, alpha SubunitInflammation MediatorsNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, ratTriose-Phosphate Isomerasecollagen-induced arthritis (CIA)glycolysismetabolism reprogrammingmonocytesnicotinamide phosphoribosyltransferase (NAMPT)rheumatoid arthritis (RA)triosephosphate isomerase 1 (TPI1)

Identifiers

PMID35111160
PMCPMC8801790
OpenAlexW4206839773

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.