Evidence map›Paper›PMID 35111151›Full record

ArticleFrontiers in immunology2021

Characterization of Leptin Receptor

Liwei Jiang, Mine Yilmaz, Mayuko Uehara, Cecilia B Cavazzoni, Vivek Kasinath, Jing Zhao, Said Movahedi Naini, Xiaofei Li, Naima Banouni, Paolo Fiorina and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Liwei JiangTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Mine YilmazTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Mayuko UeharaTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Cecilia B CavazzoniTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Vivek KasinathTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Jing ZhaoTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Said Movahedi NainiTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Xiaofei LiTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Naima BanouniTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Paolo FiorinaDivision of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Su Ryon ShinBiomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, United States.
Stefan G TulliusDivision of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Jonathan S BrombergDepartments of Surgery and Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, United States.
Peter T SageTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Reza AbdiTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Harvard University · USBrigham and Women's Hospital · USInnovation Research Center · USUniversity of Maryland, Baltimore · US

Funding

Reshaping lymph node stroma for transplant toleranceP01AI153003 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jonathan S Bromberg · 2020 to 2026
$9.3M
Lymph Node Structure and Function in Tolerance: Role of LamininsR01AI114496 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BROMBERG, JONATHAN S · 2015 to 2024
$4.2M
A novel approach to delivering therapeutics in heart transplantationR01HL145813 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2019 to 2022
$2.6M
Protection of organ transplant from ischemia reperfusion injuriesR01AI126596 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2016 to 2020
$2.6M
Senescent cells drive mt-DNA accumulation and inflamm-agingR01AG064165 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI TULLIUS, STEFAN GUNTHER · 2020 to 2024
$2.6M
IRI, innate immunity and transplant rejectionR01AI156084 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2021 to 2025
$2.3M
PI3K-gamma regulates T cell mediated alloimmunityR01HL141815 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2018 to 2021
$1.6M
Developing novel biomarkers of renal transplant rejectionK24AI116925 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2016 to 2023
$1.4M
NHLBI NIH HHS R01 HL141815NHLBI NIH HHS R01 HL145813NIAID NIH HHS K24 AI116925NIAID NIH HHS P01 AI153003NIAID NIH HHS R01 AI114496NIAID NIH HHS R01 AI126596NIAID NIH HHS R01 AI156084NIA NIH HHS R01 AG064165
6 · The paper itself

Abstract

Lymph node (LN)-resident stromal cells play an essential role in the proper functioning of LNs. The stromal compartment of the LN undergoes significant compensatory changes to produce a milieu amenable for regulation of the immune response. We have identified a distinct population of leptin receptor-expressing (LepR

Indexed as

AnimalsCell LineDendritic Cells, FollicularEndotheliumExtracellular MatrixFibroblastsImmunityInflammationLymphatic VesselsLymph NodesMiceReceptors, LeptinSignal TransductionStromal CellsVenulesReceptors, Leptinleptin receptorlymph nodematrix structurestromal celltype 2 diabetes

Identifiers

PMID35111151
PMCPMC8801441
OpenAlexW4205385844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.