Evidence map›Paper›PMID 35111134›Full record

ArticleFrontiers in endocrinology2021

Independent Variables for Determining the Cumulative Live Birth Rates of Aged Patients with Polycystic Ovary Syndrome or Tubal Factor Infertility: A Retrospective Cohort Study.

Yichun Guan, Pingping Kong, Zhiying Xiao, Junyan Zhang, Jingfang He, Wenjun Geng, Junfang Yan, Simin Sun, Mingkun Mu, Xiaofang Du and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yichun GuanThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Pingping KongThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhiying XiaoThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Junyan ZhangTraining Department, Bothwin Clinical Research Consultants, Redmond, WA, United States.
Jingfang HeTraining Department, Bothwin Clinical Research Consultants, Redmond, WA, United States.
Wenjun GengThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Junfang YanThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Simin SunThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mingkun MuThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiaofang DuThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xingling WangThe Reproduction Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Third Affiliated Hospital of Zhengzhou University · CNClinical Research Consultants (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess whether women of advanced age (≥35 years) with polycystic ovary syndrome (PCOS) have the same cumulative live birth rate (CLBR) as their age-matched controls with tubal factor infertility and to determine the influencing factors on the CLBRs of aged women. Design: A retrospective cohort study. Setting and Population: A total of 160 women of advanced age (≥35 years) with PCOS and 1073 women with tubal factor infertility were included in our study. All patients underwent their first fresh cycles and subsequent frozen cycles within in one year in our centre from 2015 to 2020. Methods: To determine independent influencing factors on the CLBRs of these aged patients, a multivariable Cox regression model of CLBR according to the transfer cycle type was constructed. Result: The Cox regression model of the CLBRs indicated that there was no significant difference between the PCOS group and the tubal infertility group in terms of advanced age (HR, 0.95; 95% CI, 0.71-1.27, Conclusion: Despite the higher number of oocytes retrieved in PCOS patients, the reproductive window is not extended for PCOS patients compared with tubal factor infertility patients. Age, AMH and the number of oocytes retrieved play crucial roles in the CLBRs of patients of advanced age (≥35 years).

Indexed as

Pregnancy RateAdultAnti-Mullerian HormoneCase-Control StudiesCohort StudiesEmbryo TransferFallopian Tube DiseasesFemaleFertilization in VitroHumansInfertility, FemaleLive BirthPolycystic Ovary SyndromePregnancyRetrospective StudiesSperm Injections, IntracytoplasmicAnti-Mullerian Hormone≥35 yearsadvanced agecumulative live birth ratespolycystic ovary syndrometubal factor infertility

Identifiers

PMID35111134
PMCPMC8803204
OpenAlexW4206766793

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.