Evidence map›Paper›PMID 35111076›Full record

ArticleFrontiers in physiology2021

Natriuresis During an Acute Intravenous Sodium Chloride Infusion in Conscious Sprague Dawley Rats Is Mediated by a Blood Pressure-Independent α

Alissa A Frame, Kayla M Nist, Kiyoung Kim, Jill T Kuwabara, Richard D Wainford

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alissa A FrameDepartment of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, United States.
Kayla M NistWhitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA, United States.
Kiyoung KimDepartment of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, United States.
Jill T KuwabaraDepartment of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, United States.
Richard D WainfordDepartment of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, United States.
Boston University · US

Funding

Aging and hypertension: Integrated renal and sympathetic control of blood pressureR01AG062515 · NIA · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2019 to 2023
$3.5M
Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressureR01HL141406 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.8M
Neural control of the kidney and long-term blood pressure regulationR01HL139867 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.6M
NHLBI NIH HHS R01 HL139867NHLBI NIH HHS R01 HL141406NIA NIH HHS R01 AG062515
6 · The paper itself

Abstract

The mechanisms that sense alterations in total body sodium content to facilitate sodium homeostasis in response to an acute sodium challenge that does not increase blood pressure have not been fully elucidated. We hypothesized that the renal sympathetic nerves are critical to mediate natriuresis via α

Indexed as

adrenoceptorsnatriuresispressure-natriuresisrenal sympathetic nervessodium homeostasis

Identifiers

PMID35111076
PMCPMC8802910
OpenAlexW4205862183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.