Evidence map›Paper›PMID 35111014›Full record

ArticleCase reports in oncology

Occult Disseminated Metastatic Breast Carcinoma Presenting as Acquired Thrombotic Thrombocytopenic Purpura.

Siew Lian Chong, Asral Wirda Ahmad Asnawi, Roszymah Hamzah, Pek Kuen Liew, Tee Chuan Ong, Sen Mui Tan, Kian Meng Chang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Siew Lian ChongDepartment of Hematology, Hospital Ampang, Ampang, Malaysia.
Asral Wirda Ahmad AsnawiDepartment of Hematology, Hospital Ampang, Ampang, Malaysia.
Roszymah HamzahDepartment of Hematology, Hospital Ampang, Ampang, Malaysia.
Pek Kuen LiewDepartment of Hematology, Hospital Ampang, Ampang, Malaysia.
Tee Chuan OngDepartment of Hematology, Hospital Ampang, Ampang, Malaysia.
Sen Mui TanDepartment of Hematology, Hospital Ampang, Ampang, Malaysia.
Kian Meng ChangDepartment of Medicine, Sunway Medical Centre, Petaling Jaya, Malaysia.
KPJ Ampang Puteri Specialist Hospital · MYUniversiti Sains Islam Malaysia · MYSunway University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-related microangiopathic hemolytic anemia (MAHA) is a rare and life-threatening condition. We present a patient who had been treated for invasive lobular breast carcinoma in clinical remission with fever and hemolytic anemia. The peripheral blood film showed MAHA and thrombocytopenia, and a functional deficiency of ADAMTS13 activity of 23% consistent with acquired thrombotic thrombocytopenic purpura. Bone marrow aspirate and trephine biopsy confirmed metastatic carcinoma. Further evaluation revealed the involvement of multiple bone sites without recurrence of the primary tumor. The patient received a daily plasma exchange with cryosupernatant and was pulsed with corticosteroids. MAHA related to breast cancer appears to be a rare occurrence.

Indexed as

ADAMTS13CarcinomaHemolysisMicroangiopathyThrombotic thrombocytopenic purpura

Identifiers

PMID35111014
PMCPMC8787534
OpenAlexW4200542908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.