ReviewFrontiers in neuroscience2021
The Autism Phenome Project: Toward Identifying Clinically Meaningful Subgroups of Autism.
Review in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Heterogeneity of Response to Early Start Denver Model: Identifying Developmental Trajectories and Predictors of Cognitive Outcomes.Autism research : official journal of the International Society for Autism Research · 2026Article
- Multimodal predictors of spoken vocabulary development in autism: the role of early childhood brain and behavior.Translational psychiatry · 2026Article
- One Size Doesn't Fit All: Variability in Autistic Children's Response to Pivotal Response Treatment.Behavioral sciences (Basel, Switzerland) · 2025Article
- Later Age of Autism Diagnosis in Children with Multiple Co-Occurring Psychiatric Disorders.Journal of autism and developmental disorders · 2025Article
- Hypothalamic volume is associated with dysregulated sleep in autistic and non-autistic young children.Autism : the international journal of research and practice · 2025Article
- Article
- Trajectories of autism symptom severity for boys and girls across childhood.Autism : the international journal of research and practice · 2025Article
- Sex Differences in the Striatal Contributions to Longitudinal Fine Motor Development in Autistic Children.Biological psychiatry · 2025Article
- Subgrouping autism and ADHD based on structural MRI population modelling centiles.Molecular autism · 2025Article
- The Possible Role of Postnatal Biphasic Dysregulation of IGF-1 Tone in the Etiology of Idiopathic Autism Spectrum Disorder.International journal of molecular sciences · 2025Review
- mAutism research : official journal of the International Society for Autism Research · 2025Article
- Sensorimotor Features and Daily Living Skills in Autistic Children With and Without ADHD.Journal of autism and developmental disorders · 2025Observational
- Cortical Thickness Differences in Autistic Children With and Without Intellectual Disability.Autism research : official journal of the International Society for Autism Research · 2025Article
- Multiparametric Assays Capture Sex- and Environment-Dependent Modifiers of Behavioral Phenotypes in Autism Mouse Models.Biological psychiatry global open science · 2024Article
- Sex differences in trajectories of cortical development in autistic children from 2-13 years of age.Molecular psychiatry · 2024Article
- Changes in the severity of autism symptom domains are related to mental health challenges during middle childhood.Autism : the international journal of research and practice · 2024Article
- Structural Brain Imaging Biomarkers of Autism Spectrum Disorder.Advances in neurobiology · 2024Review
- Review
- Habituation of auditory responses in young autistic and neurotypical children.Autism research : official journal of the International Society for Autism Research · 2023Article
- Why do we need sex-balanced studies of autism?Autism research : official journal of the International Society for Autism Research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most universally accepted facts about autism is that it is heterogenous. Individuals diagnosed with autism spectrum disorder have a wide range of behavioral presentations and a variety of co-occurring medical and mental health conditions. The identification of more homogenous subgroups is likely to lead to a better understanding of etiologies as well as more targeted interventions and treatments. In 2006, we initiated the UC Davis MIND Institute Autism Phenome Project (APP) with the overarching goal of identifying clinically meaningful subtypes of autism. This ongoing longitudinal multidisciplinary study now includes over 400 children and involves comprehensive medical, behavioral, and neuroimaging assessments from early childhood through adolescence (2-19 years of age). We have employed several strategies to identify sub-populations within autistic individuals: subgrouping by neural, biological, behavioral or clinical characteristics as well as by developmental trajectories. In this Mini Review, we summarize findings to date from the APP cohort and describe progress made toward identifying meaningful subgroups of autism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.