Evidence map›Paper›PMID 35110976›Full record

ArticleDose-response : a publication of International Hormesis Society

Puerarin Reduces Radiation-Induced Vascular Endothelial Cell Damage Via miR-34a/Placental Growth Factor.

Chang Liu, Ying Zhao, Xiaoting Xu, Lei Zhang, Fengmei Cui, Qiu Chen, Hongxia Li, Ru Sang, Gen Li, Yongming He

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chang LiuDepartment of Cardiology, First Affiliated Hospital of Soochow University, Suzhou, China.
Ying ZhaoState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Xiaoting XuDepartment of Radiotherapy & Oncology, First Affiliated Hospital of Soochow University, Suzhou, China.
Lei ZhangDepartment of Cardiology, First Affiliated Hospital of Soochow University, Suzhou, China.
Fengmei CuiState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0001-8542-3552
Qiu ChenState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Hongxia LiDepartment of Cardiology, First Affiliated Hospital of Soochow University, Suzhou, China.
Ru SangDepartment of Radiotherapy & Oncology, First Affiliated Hospital of Soochow University, Suzhou, China.
Gen LiState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Yongming HeDepartment of Cardiology, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0003-3154-2892
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim is to explore the protective effects of Puerarin on radiation-induced vascular endothelial cell damage and its underlying mechanism. The apoptosis and DNA damage of Human umbilical vascular endothelial cells (HUVECs) exposed to radiation alone or in combination with glucose in the exposed group were significantly elevated (

Indexed as

human umbilical vascular endothelial cellsmiR-34aplacental growth factorpuerarinradiation

Identifiers

PMID35110976
PMCPMC8796097
OpenAlexW4205920271

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.