Evidence map›Paper›PMID 35110956›Full record

ArticleWorld journal of gastroenterology2022

Postoperative mortality and morbidity after D2 lymphadenectomy for gastric cancer: A retrospective cohort study.

Giuseppe Brisinda, Maria Michela Chiarello, Anna Crocco, Neill James Adams, Pietro Fransvea, Serafino Vanella

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
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  10. Indocyanine green: The guide to safer and more effective surgery.World journal of gastrointestinal surgery · 2024
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  11. Review
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  17. Early gastric cancer: A challenge in Western countries.World journal of gastroenterology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Giuseppe BrisindaAbdominal Surgery, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome 00168, Italy.
Maria Michela ChiarelloGeneral Surgery Operative Unit, Azienda Sanitaria Provinciale di Crotone, Ospedale San Giovanni di Dio, Crotone 88900, Italy.
Anna CroccoEndocrine Surgery Operative Unit, Istituto Nazionale Tumori, IRCCS Fondazione Pascale, Napoli 80100, Italy.
Neill James AdamsHealth Sciences, Clinical Microbiology Unit, Magna Grecia University, Catanzaro 88100, Italy.
Pietro FransveaDepartment of Emergency Surgery and Trauma Center, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome 00168, Italy.
Serafino VanellaDepartment of General and Oncological Surgery, Azienda Ospedaliera San Giuseppe Moscati, Avellino 83100, Italy.
Agostino Gemelli University Polyclinic · ITAzienda Ospedaliera S.Giuseppe Moscati · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITMagna Graecia University · ITNuovo Ospedale San Giovanni di Dio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgery for gastric cancer is a complex procedure and lymphadenectomy is often mandatory. Postoperative mortality and morbidity after curative gastric cancer surgery is not insignificant.

aimTo evaluate the factors determining mortality and morbidity in a population of patients undergoing R0 resection and D2 lymphadenectomy for gastric cancer.

methodsA retrospective analysis of clinical data and pathological characteristics (age, sex, primary site of the tumor, Lauren histotype, number of positive lymph nodes resected, number of negative lymph nodes resected, and depth of invasion as defined by the standard nomenclature) was conducted in patients with gastric cancer. For each patient we calculated the Kattan's score. We arbitrarily divided the study population of patients into two groups based on the nomogram score (< 100 points or ≥ 100 points). Prespecified subgroups in these analyses were defined according to age (≤ 65 years or > 65 years), and number of lymph nodes retrieved (≤ 35 lymph nodes or > 35 lymph nodes). Uni- and multivariate analysis of clinical and pathological findings were performed to identify the factors affecting postoperative mortality and morbidity.

resultsOne-hundred and eighty-six patients underwent a curative R0 resection with D2 lymphadenectomy. Perioperative mortality rate was 3.8% (7 patients); a higher mortality rate was observed in patients aged > 65 years (

conclusionMortality and morbidity rate are higher in N+ and advanced gastric cancer patients. The removal of more than 35 lymph nodes does not lead to an increase in mortality.

Indexed as

Stomach NeoplasmsAgedGastrectomyHumansLymphatic MetastasisLymph Node ExcisionMorbidityRetrospective StudiesAnastomotic leakageGastric cancerHemoperitoneumKattan’s nomogramLymphadenectomyMortalityPostoperative complicationsPostoperative pancreatic fistulaSubtotal gastrectomyTotal gastrectomy

Identifiers

PMID35110956
PMCPMC8771610
OpenAlexW4206193619

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.