Evidence map›Paper›PMID 35110955›Full record

ArticleWorld journal of gastroenterology2022

Microbiome changes in the gastric mucosa and gastric juice in different histological stages of

Qing-Hua Sun, Jing Zhang, Yan-Yan Shi, Jing Zhang, Wei-Wei Fu, Shi-Gang Ding

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. The emerging role of non-Gastroenterology report · 2026
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  6. Signaling pathways and targeted interventions for precancers.Signal transduction and targeted therapy · 2026
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  7. Gastro hep advances · 2026
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  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Observational
  14. Ex Vivo Analysis of the Effect of Endoscopic Premedications on the Microbiota Profile in Gastric Juice.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. The influence ofComputational and structural biotechnology journal · 2024
    Review
  19. Exploring the Link betweenAntibiotics (Basel, Switzerland) · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qing-Hua SunDepartment of Gastroenterology, Peking University Third Hospital, Beijing 100191, China.
Jing ZhangDepartment of Gastroenterology, Peking University Third Hospital, Beijing 100191, China.
Yan-Yan ShiResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing 10019, China.
Jing ZhangDepartment of Gastroenterology, Peking University Third Hospital, Beijing 100191, China.
Wei-Wei FuDepartment of Gastroenterology, Peking University Third Hospital, Beijing 100191, China.
Shi-Gang DingDepartment of Gastroenterology, Peking University Third Hospital, Beijing 100191, China. dingshigang222@163.com.
Peking University · CNPeking University Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe gastric microbiota in patients with gastric cancer (GC) has received increasing attention, but the profiling of the gastric microbiome through the histological stages of gastric tumorigenesis remains poorly understood, especially for patients with

aimTo characterize microbial profiles of gastric mucosa and juice for HPNGC carcinogenesis and identify distinct taxa in precancerous lesions.

methodsThe 16S rRNA gene analysis was performed on gastric mucosa from 134

resultsThe diversity and composition of the bacterial microbiota in the gastric mucosa changed progressively across stages of gastric carcinogenesis. The diversity of the gastric mucosa microbiota was found to be significantly lower in the IM and Dys groups than in the SG group, and the patients with GC had the lowest bacterial community richness (

conclusionOur results provide insights into potential taxonomic biomarkers for HPNGC and its precancerous stages and assist in predicting the prognosis of IM and Dys based on the mucosal microbiota profile.

Indexed as

Helicobacter InfectionsHelicobacter pyloriMicrobiotaStomach NeoplasmsGastric JuiceGastric MucosaHumansRNA, Ribosomal, 16SRNA, Ribosomal, 16S16s RNA gene sequencingGastric juiceGastric mucosaHistological stagesMicrobiotaStomach neoplasms

Identifiers

PMID35110955
PMCPMC8771614
OpenAlexW4205089181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.