Evidence map›Paper›PMID 35110948›Full record

Observational studyWorld journal of gastroenterology2022

Identification of functional tumor necrosis factor-alpha promoter variants associated with

Abeer Babiker Idris, Alaa B Idris, Manal A Gumaa, Mohammed Babiker Idris, Amanda Elgoraish, Mohamed Mansour, Dalia Allam, Bashir Mo Arbab, Nazar Beirag, El-Amin M Ibrahim and 1 more

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Abeer Babiker IdrisDepartment of Agricultural Science and Technology, Institute of Natural and Applied Sciences, Erciyes University, Kayseri 38039, Turkey.
Alaa B IdrisDepartment of Neurosurgery, Ribat University Hospital, Khartoum 11111, Sudan.
Manal A GumaaDepartment of Medical Microbiology, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum 11111, Sudan.
Mohammed Babiker IdrisBioMérieux Clinical and Application Advisor, Al-Jeel Medical Co., Riyadh 11422, Saudi Arabia.
Amanda ElgoraishDepartment of Epidemiology, Tropical Medicine Research Institute, Khartoum 11111, Sudan.
Mohamed MansourDepartment of Gastroenterology, Ibn Sina Specialized Hospital, Khartoum 11111, Sudan.
Dalia AllamDepartment of Gastroenterology, Ibn Sina Specialized Hospital, Khartoum 11111, Sudan.
Bashir Mo ArbabDepartment of Gastroenterology, Modern Medical Centre, Khartoum 11111, Sudan.
Nazar BeiragBiosciences, College of Health, Medicine and Life Sciences, Brunel University, London UB8 3PH, Uxbridge, United Kingdom.
El-Amin M IbrahimDepartment of Medical Microbiology, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum 11111, Sudan.
Mohamed A HassanDepartment of Bioinformatics, Africa city of technology, Khartoum 11111, Sudan.
Ibn Sina Hospital · KWNational Ribat University · SDUniversity of Medical Sciences and Technology · SDBrunel University of London · GBInternational University of Africa · SDNational Centre for Research · SDRiyadh Armed Forces Hospital · SASudan Medical Specialization Board · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

aimTo functionally characterize the genetic variations in the

methodsAn observational study was carried out in major public and private hospitals in Khartoum state. A total of 122 gastric biopsies were taken from patients who had been referred for endoscopy. Genomic DNA was extracted. Genotyping of the

resultsA total of seven single nucleotide polymorphisms were observed in the

conclusionComputational analysis was a valuable method for understanding

Indexed as

Helicobacter InfectionsHelicobacter pyloriGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotidePromoter Regions, GeneticTumor Necrosis Factor-alphaTumor Necrosis Factor-alpha5’-regionHelicobacter pyloriIn silico analysisPromoterSudanTNF-A

Identifiers

PMID35110948
PMCPMC8776532
OpenAlexW4206770399

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.