ArticleIndian journal of surgical oncology2021
Resection of Asymptomatic Primary Tumor with Synchronous Unresectable Colorectal Metastasis-Is It Reasonable?
Article in Indian journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As much as 30% of colorectal cancers at presentation may have distant metastasis. Asymptomatic primary tumors in the face of synchronous, unresectable metastasis are usually treated with systemic therapy alone. However, data to support or reject primary tumor resection exists and we are yet to come to a definite conclusion. Multiple randomized trials that attempted to address this question failed to accrue adequate patients. The more recent Japanese trial, however, demonstrated a small detriment in overall survival with primary tumor resection. Early cessation of trial with subsequent underpowered results and lack of representation of rectal tumors are key drawbacks of this study. Finally, a balance has to be struck between the risks of tumor-relatedcomplications on systemic therapy with consequent emergency operative morbidity and that of delays in systemic therapy due to primary tumor resection upfront.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.