ArticleProceedings of the National Academy of Sciences of the United States of America2022
Domoic acid biosynthesis in the red alga
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- Tracing the origin and evolution of specialized biosynthetic pathways in marine organisms.mBio · 2026Article
- A high-throughput biocatalytic platform for screening isomeric kainoid natural products.Cell reports. Physical science · 2026Article
- Aptamer-Based Dual-Cascade Signal Amplification System Lights up G-Quadruplex Dimers for Ultrasensitive Detection of Domoic Acid.Marine drugs · 2026Article
- Molecular and Cellular Mechanisms Underlying Domoic Acid-Induced Neurotoxicity and Therapeutic Drugs: A Comprehensive Review.International journal of molecular sciences · 2026Review
- Some Bioactive Natural Products from Diatoms: Structures, Biosyntheses, Biological Roles, and Properties: 2015-2025.Marine drugs · 2026Review
- Article
- A High-Throughput Biocatalytic Platform for Screening Isomeric Kainoid Natural Products.bioRxiv : the preprint server for biology · 2025Article
- A widespread metabolic gene cluster family in metazoans.Nature chemical biology · 2025Article
- Multiple Catalytic Branch Points in the Mechanism of Pyrrolidine Formation During Kainoid Biosynthesis Leads to Diverse Reaction Outcomes.Journal of the American Chemical Society · 2025Article
- Discovery of Noncanonical Iron and 2-Oxoglutarate Dependent Enzymes Involved in C-C and C-N Bond Formation in Biosynthetic Pathways.ACS bio & med chem Au · 2025Review
- Acquisition and evolution of the neurotoxin domoic acid biosynthesis gene cluster in Pseudo-nitzschia species.Communications biology · 2024Article
- Molecular forecasting of domoic acid during a pervasive toxic diatom bloom.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Molecular Dynamics Simulation Reveal the Structure-Activity Relationships of Kainoid Synthases.Marine drugs · 2024Article
- Biosynthesis of Haloterpenoids in Red Algae via Microbial-like Type I Terpene Synthases.ACS chemical biology · 2024Article
- Expression, purification, and biochemical characterization of micro- and macroalgal kainoid synthases.Methods in enzymology · 2024Article
- Algal Kainoid Synthases Exhibit Substrate-Dependent Hydroxylation and Cyclization Activities.ACS chemical biology · 2023Article
- Prolonged, Low-Level Exposure to the Marine Toxin, Domoic Acid, and Measures of Neurotoxicity in Nonhuman Primates.Environmental health perspectives · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Domoic acid (DA), the causative agent of amnesic shellfish poisoning, is produced by select organisms within two distantly related algal clades: planktonic diatoms and red macroalgae. The biosynthetic pathway to isodomoic acid A was recently solved in the harmful algal bloom-forming diatom
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.