Evidence map›Paper›PMID 35110388›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

ADAM17 Regulates p75

Marta Pellegatta, Paolo Canevazzi, Maria Grazia Forese, Paola Podini, Serena Valenzano, Ubaldo Del Carro, Angelo Quattrini, Carla Taveggia

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. iRhom2 deletion protects against diabetic neuropathy by suppressing neuroinflammation.The Journal of pharmacology and experimental therapeutics · 2026
    Article
  4. Article
  5. Peripheral nerve injury reduces macrophage efferocytosis to facilitate neuropathic pain.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. TFEB/3 Govern Repair Schwann Cell Generation and Function Following Peripheral Nerve Injury.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marta PellegattaInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy pellegatta.marta@hsr.it taveggia.carla@hsr.it.
Paolo CanevazziInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy.
Maria Grazia ForeseInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy.
Paola PodiniInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy.
Serena ValenzanoInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy.
Ubaldo Del CarroInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy.
Angelo QuattriniInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy.
Carla TaveggiaInstitute of Experimental Neurology, Division of Neuroscience, San Raffaele Research Hospital, Milan 20132, Italy pellegatta.marta@hsr.it taveggia.carla@hsr.it.ORCID 0000-0002-6531-9544
San Raffaele University of Rome · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that a-disintegrin and metalloproteinase (ADAM)17 is a key protease regulating myelin formation. We now describe a role for ADAM17 during the Wallerian degeneration (WD) process. Unexpectedly, we observed that glial ADAM17, by regulating p75

Indexed as

ADAM17 ProteinReceptor, Nerve Growth FactorRemyelinationAnimalsDisintegrinsFibrinFibrinolysisMiceTissue Plasminogen ActivatorWallerian DegenerationADAM17 ProteinAdam17 protein, mouseDisintegrinsFibrinReceptor, Nerve Growth FactorTissue Plasminogen ActivatorADAM17fibrinolysisp75NTRremyelinationSchwann cellWallerian degeneration

Identifiers

PMID35110388
PMCPMC8944234
OpenAlexW4210586884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.