Evidence map›Paper›PMID 35110339›Full record

ArticleSaudi medical journal2022

Survival and prognostic factors in women treated for epithelial ovarian cancer in western region of Saudi Arabia.

Khalid H Sait, Mohammad Z Alam, Absarul Haque, Hesham K Sait, Maram K Sait, Nisreen M Anfinan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Khalid H SaitFrom the Gynecology Oncology Unit, Obstetrics and Gynecology Department (Sait K, Sait H, Anfinan), form the Faculty of Medicine (Sait K, Sait H, Sait M), King Abdulaziz University; and from the Stem cell Unit Oncology Unit, Department of Medical Laboratory Technology (Alam, Haque), King Fahd Medical Research Center and Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Mohammad Z AlamFrom the Gynecology Oncology Unit, Obstetrics and Gynecology Department (Sait K, Sait H, Anfinan), form the Faculty of Medicine (Sait K, Sait H, Sait M), King Abdulaziz University; and from the Stem cell Unit Oncology Unit, Department of Medical Laboratory Technology (Alam, Haque), King Fahd Medical Research Center and Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Absarul HaqueFrom the Gynecology Oncology Unit, Obstetrics and Gynecology Department (Sait K, Sait H, Anfinan), form the Faculty of Medicine (Sait K, Sait H, Sait M), King Abdulaziz University; and from the Stem cell Unit Oncology Unit, Department of Medical Laboratory Technology (Alam, Haque), King Fahd Medical Research Center and Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Hesham K SaitFrom the Gynecology Oncology Unit, Obstetrics and Gynecology Department (Sait K, Sait H, Anfinan), form the Faculty of Medicine (Sait K, Sait H, Sait M), King Abdulaziz University; and from the Stem cell Unit Oncology Unit, Department of Medical Laboratory Technology (Alam, Haque), King Fahd Medical Research Center and Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Maram K SaitFrom the Gynecology Oncology Unit, Obstetrics and Gynecology Department (Sait K, Sait H, Anfinan), form the Faculty of Medicine (Sait K, Sait H, Sait M), King Abdulaziz University; and from the Stem cell Unit Oncology Unit, Department of Medical Laboratory Technology (Alam, Haque), King Fahd Medical Research Center and Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Nisreen M AnfinanFrom the Gynecology Oncology Unit, Obstetrics and Gynecology Department (Sait K, Sait H, Anfinan), form the Faculty of Medicine (Sait K, Sait H, Sait M), King Abdulaziz University; and from the Stem cell Unit Oncology Unit, Department of Medical Laboratory Technology (Alam, Haque), King Fahd Medical Research Center and Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
SAIT Polytechnic · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess survival and prognostic factors among women with epithelial ovarian cancer in Western Saudi Arabia.

methodsA retrospective cohort study was carried out between October 2000 and May 2018, reviewing clinical and pathology data of all women who underwent staging or debulking surgery for epithelial ovarian cancer. Analysis of disease-free survival (DFS), overall survivals (OS) and the associated factors used Kaplan-Meier method in addition to cox multivariate regression.

resultsA total of 144 patients were included (median age=49.5 years), with a median follow-up time was 3.4 years. Majority (59.7%) of the patients were diagnosed at an advanced stage (III or IV). The mean (95% CI) DFS was 82.3 (67.8-96.8) months, OS was 96.2 (81.3-111.2) months, and the 5-year survival rate was estimated as 38.9%. Univariate analysis showed that older age, clear cell or papillary carcinoma subtypes, serous type, advanced International Federation of Gynecology and Obstetrics (FIGO) stage and the presence of residual disease were associated with poorer DFS and OS (log rank <0.05). Cox regression showed FIGO stage and residual disease >1cm as the strongest prognostic factors independently associated with DFS and OS.

conclusionImproving early diagnosis and achieving optimal cytoreduction are the most critical challenges to achieve significant positive impact on survival of women with epithelial ovarian cancer.

Indexed as

Ovarian NeoplasmsAgedCarcinoma, Ovarian EpithelialFemaleHumansMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesSaudi Arabiaepithelialovarian cancerSaudi Arabiasurvival

Identifiers

PMID35110339
PMCPMC9127918
OpenAlexW4210504490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.