Evidence map›Paper›PMID 35110289›Full record

ArticleBMJ case reports2022

Reversible radiculomyelitis after ChAdOx1 nCoV-19 vaccination.

Rossella Spataro, Giacomo Fisco, Vincenzo La Bella

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Co-VAN study: COVID-19 vaccine associated neurological diseases- an experience from an apex neurosciences centre and review of the literature.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rossella SpataroDepartment of Biomedicine, Neuroscience and Advanced Diagnostics, ALS Clinical Research Center, University of Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0002-8910-3131
Giacomo FiscoIRCCS Centro Neurolesi Bonino Pulejo, Palermo, Italy.
Vincenzo La BellaDepartment of Biomedicine, Neuroscience and Advanced Diagnostics, ALS Clinical Research Center, University of Palermo, Palermo, Italy vincenzo.labella@unipa.it.ORCID http://orcid.org/0000-0003-2045-1864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse events occurring after SARS-CoV-2 vaccination have been reported and are the subject of ongoing research. We present the case of a young woman with fully reversible radiculomyelitis, which happened after the first dose of the ChAdOx1 nCOVID-19 vaccine. A previously healthy woman in her 20s presented with a subacute onset of legs' weakness and sensory disturbances, urinary dysfunction and cramping pain after receiving the first dose of the ChAdOx1 nCoV-19 vaccine. A diagnostic workup led to the diagnosis of inflammatory radiculomyelitis. Her clinical status improved, with complete recovery after a few months. The case described a reversible radiculomyelitis associated with the ChAdOx1 nCOVID-19 vaccine. The clinical picture and evolution supported the diagnosis. No other identifiable causes of myelopathy were found. Our patient showed clinically moderate symptoms and signs, showing good recovery. The post-vaccine inflammatory radiculomyelitis is a rare side effect of the anti-COVID-19 vaccination, and it should not discourage the SARS-CoV-2 vaccination programme.

Indexed as

COVID-19Viral VaccinesChAdOx1 nCoV-19COVID-19 VaccinesFemaleHumansSARS-CoV-2VaccinationChAdOx1 nCoV-19COVID-19 VaccinesViral VaccinesCOVID-19infection (neurology)spinal cord

Identifiers

PMID35110289
PMCPMC8811582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.