Evidence map›Paper›PMID 35110026›Full record

ArticleTurkish journal of anaesthesiology and reanimation2021

Effects of calcitonin addition on epidural injection in patients with degenerative spinal canal stenosis: a randomized double blind clinical trial.

Poupak Rahimzadeh, Seyed Mani Mahdavi, Kamran Mahmoudi, Hassan Ghandhari, Ali Babashahi, Parvaneh Zandi, Seyed Hamid Reza Faiz

Open access · greenAbstract read
In one paragraph

Article in Turkish journal of anaesthesiology and reanimation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Effects of calcitonin on lumbar spinal stenosis.Archives of orthopaedic and trauma surgery · 2024
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Poupak RahimzadehPain Research Center, Iran University of Medical Sciences, Tehran, Iran.
Seyed Mani MahdaviDepartment of Orthopedic Surgery, Iran University of Medical Sciences, Tehran, Iran.
Kamran MahmoudiDepartment of Anesthesiology, Ahwaz University of Medical Sciences, Ahwaz, Iran.
Hassan GhandhariDepartment of Orthopedic Surgery, Iran University of Medical Sciences, Tehran, Iran.
Ali BabashahiDepartment of Neurosurgery, Iran University of Medical Sciences, Tehran, Iran.
Parvaneh ZandiPain Research Center, Iran University of Medical Sciences, Tehran, Iran.
Seyed Hamid Reza FaizPain Research Center, Iran University of Medical Sciences, Tehran, Iran.
Iran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBack pain is reported to be the fifth most common reason for referral a patient to a physician and the most common disability in modern society. The present study aimed to evaluate the effects of calcitonin addition on epidural injection in patients with degenerative spinal canal stenosis in comparison with epidural triamcinolone injection. MATERIALS AND

methodsThe clinical trial study was performed on 40 patients with degenerative spinal stenosis, referred to pain clinic of RasoulAkram Hospital in 2018, who were randomly divided into two intervention and control groups, including 20 individuals in each group. In the intervention group, 50 units of calcitonin were injected with 8 cc of ropivacaine 0.2% while 80 mg of triamcinolone with 8 cc of ropivacaine 0.2% was injected in the control group. Functional disability was evaluated based on the Oswestry Disability Index (ODI) and pain ratings were assessed using the Visual Analogue Scale (VAS).

resultsPain at 4 and 8 weeks after the procedure was significantly different between the two groups. A significant difference in the patient disability index was observed between two groups at 8 and 12 weeks after the procedure. On the other hand, the rate of analgesic consumption at 4, 8 and 12 weeks after the procedure was significantly decreased in the calcitonin group (P <0.001).

conclusionsBased on our results, injection of calcitonin into the epidural space can reduce the pain of the patients and their analgesic consumption compared to the group receiving steroids through the epidural space.

Identifiers

PMID35110026
PMCPMC9472690
OpenAlexW3160641187

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.