Evidence map›Paper›PMID 35109772›Full record

ArticleEmerging microbes & infections2022

Resistance profiling of

Jochem B Buil, Jason D Oliver, Derek Law, Tim Baltussen, Jan Zoll, Margriet W J Hokken, Marlou Tehupeiory-Kooreman, Willem J G Melchers, Mike Birch, Paul E Verweij

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Olorofim activity against multidrug-resistantAntimicrobial agents and chemotherapy · 2025
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  10. Antimicrobial agents and chemotherapy · 2025
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  12. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  13. Refractory versus resistant invasive aspergillosis.The Journal of antimicrobial chemotherapy · 2025
    Review
  14. Innovative antifungal strategies to combat drug-resistantFrontiers in cellular and infection microbiology · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Jochem B BuilDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Jason D OliverF2G Ltd, Manchester, UK.
Derek LawF2G Ltd, Manchester, UK.
Tim BaltussenDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Jan ZollDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Margriet W J HokkenDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Marlou Tehupeiory-KooremanDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Willem J G MelchersDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Mike BirchF2G Ltd, Manchester, UK.
Paul E VerweijDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Radboud University Medical Center · NLRadboud University Nijmegen · NLUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olorofim (F901318) is a new antifungal currently under clinical development that shows both

Indexed as

Aspergillus fumigatusPyrimidinesAcetamidesAntifungal AgentsFungal ProteinsMicrobial Sensitivity TestsPiperazinesPyrrolesAcetamidesAntifungal AgentsFungal ProteinsolorofimPiperazinesPyrimidinesPyrrolesantifungal resistanceAspergillosisF901318fungalvirulence

Identifiers

PMID35109772
PMCPMC8890541
OpenAlexW4220846388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.