Evidence map›Paper›PMID 35108108›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2022

Glycine receptor subunit-β-deficiency in a mouse model of spasticity results in attenuated physical performance, growth, and muscle strength.

Cintia Rivares, Alban Vignaud, Wendy Noort, Bastijn Koopmans, Maarten Loos, Mikhail Kalinichev, Richard T Jaspers

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Muscle type-specific effects of bilateral abobotulinumtoxinA injection on muscle growth and contractile function in spastic mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  3. Inhibitory Synaptic Influences on Developmental Motor Disorders.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Cintia RivaresLaboratory for Myology, Department of Human Movement Sciences, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, The Netherlands.ORCID 0000-0002-8153-4658
Alban VignaudIpsen Innovation, Les Ulis, France.
Wendy NoortLaboratory for Myology, Department of Human Movement Sciences, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, The Netherlands.
Bastijn KoopmansSylics (Synaptologics BV), Amsterdam, The Netherlands.ORCID 0000-0001-8638-9798
Maarten LoosSylics (Synaptologics BV), Amsterdam, The Netherlands.ORCID 0000-0003-1629-2928
Mikhail KalinichevIpsen Innovation, Les Ulis, France.
Richard T JaspersLaboratory for Myology, Department of Human Movement Sciences, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, The Netherlands.ORCID 0000-0002-6951-0952
Vrije Universiteit Amsterdam · NLIpsen (France) · FRSylics (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spasticity is the most common neurological disorder associated with increased muscle contraction causing impaired movement and gait. The aim of this study was to characterize the physical performance, skeletal muscle function, and phenotype of mice with a hereditary spastic mutation (B6.Cg-Glrb

Indexed as

Cerebral PalsyMuscle SpasticityAnimalsMiceMuscle, SkeletalMuscle StrengthPhysical Functional PerformanceReceptors, GlycineReceptors, Glycinephysiological cross-sectional areaplantar flexor musclessarcomeres in seriesskeletal musclespastic paresis

Identifiers

PMID35108108
PMCPMC9054346
OpenAlexW4210459467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.