Evidence map›Paper›PMID 35108026›Full record

ArticleMolecular biology of the cell2022

Regulation of integrin α5β1 conformational states and intrinsic affinities by metal ions and the ADMIDAS.

Jordan M Anderson, Jing Li, Timothy A Springer

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Review
  7. Review
  8. MnBiophysical journal · 2025
    Article
  9. Article
  10. The role and regulation of integrins in cell migration and invasion.Nature reviews. Molecular cell biology · 2025
    Review
  11. Article
  12. Integrins as Key Mediators of Metastasis.International journal of molecular sciences · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jordan M AndersonProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
Jing LiProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
Timothy A SpringerProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
Boston Children's Hospital · US

Funding

Structures and Conformational Equilibria of Integrin alpha5 beta1R01HL131729 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI SPRINGER, TIMOTHY A · 2016 to 2024
$4.7M
NHLBI NIH HHS R01 HL131729
6 · The paper itself

Abstract

Activation of integrins by Mn

Indexed as

Integrin alpha5beta1MetalsBinding SitesCell AdhesionIntegrinsIonsLigandsProtein BindingIntegrin alpha5beta1IntegrinsIonsLigandsMetals

Identifiers

PMID35108026
PMCPMC9265148
OpenAlexW4210302581

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.